Question

I am a breastfeeding mother and i want to know if it is safe to use NSC 282126? Is NSC 282126 safe for nursing mother and child? Does NSC 282126 extracts into breast milk? Does NSC 282126 has any long term or short term side effects on infants? Can NSC 282126 influence milk supply or can NSC 282126 decrease milk supply in lactating mothers?

NSC 282126 lactation summary

NSC 282126 usage has low risk in breastfeeding
  • DrLact safety Score for NSC 282126 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of NSC 282126 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that NSC 282126 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of NSC 282126 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using NSC 282126 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NSC 282126 usage in lactation

Since the last update we have not found published data on its excretion in breast milk. Its high percentage of plasma protein binding make it very unlikely that significant amounts will pass into breast milk. Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.

Answer by DrLact: About NSC 282126 usage in lactation

Because no information is available on the use of NSC 282126 during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.