Is Agon SR Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Agon SR? Is Agon SR safe for nursing mother and child? Does Agon SR extracts into breast milk? Does Agon SR has any long term or short term side effects on infants? Can Agon SR influence milk supply or can Agon SR decrease milk supply in lactating mothers?
Agon SR lactation summary
- DrLact safety Score for Agon SR is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Agon SR may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Agon SR may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Agon SR low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Agon SR We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Agon SR usage in lactation
At latest update no published data were found on excretion into breast milk. Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount.Its high plasma protein binding capacity makes it highly unlikely a passage into milk. It has been described an increased Prolactin plasma level and gynecomastia after using Agon SR. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants.
Answer by DrLact: About Agon SR usage in lactation
Because no information is available on the use of Agon SR during breastfeeding, an alternate drug may be preferred.
Agon SR Possible Effects in Breastfeeding
Relevant published informaation was not found as of the revision date.
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Metoprolol(Safe)
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Nicardipine(Safe)
Valsartan(Low Risk)
Acebutolol(Unsafe)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Verapamil(Safe)
Nimodipine(Safe)
Cinnarizine(Low Risk)
Nifedipine(Safe)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Nitrendipine(Safe)
Nicardipine(Safe)
Diltiazem(Safe)
Verapamil(Safe)
Nimodipine(Safe)
Cinnarizine(Low Risk)
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Sildenafil(Safe)
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Nicardipine(Safe)
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Nisoldipine(Low Risk)
Isradipine(Low Risk)