Question

I am a breastfeeding mother and i want to know if it is safe to use Plendil Depottab? Is Plendil Depottab safe for nursing mother and child? Does Plendil Depottab extracts into breast milk? Does Plendil Depottab has any long term or short term side effects on infants? Can Plendil Depottab influence milk supply or can Plendil Depottab decrease milk supply in lactating mothers?

Plendil Depottab lactation summary

Plendil Depottab usage has low risk in breastfeeding
  • DrLact safety Score for Plendil Depottab is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Plendil Depottab may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Plendil Depottab may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Plendil Depottab low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Plendil Depottab We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Plendil Depottab usage in lactation

At latest update no published data were found on excretion into breast milk. Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount.Its high plasma protein binding capacity makes it highly unlikely a passage into milk. It has been described an increased Prolactin plasma level and gynecomastia after using Plendil Depottab. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants.

Answer by DrLact: About Plendil Depottab usage in lactation

Because no information is available on the use of Plendil Depottab during breastfeeding, an alternate drug may be preferred.

Plendil Depottab Possible Effects in Breastfeeding

Relevant published informaation was not found as of the revision date.

Alternate Drugs

Minoxidil(Safe)
Guanfacine(Low Risk)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Carvedilol(Low Risk)
Bisoprolol(Low Risk)
Nebivolol(Unsafe)
Enalapril(Safe)
Atenolol(Unsafe)
Lisinopril(Low Risk)
Valsartan(Low Risk)
Acebutolol(Unsafe)
Terazosin(Unsafe)
Diltiazem(Safe)
Timolol(Safe)
Nisoldipine(Low Risk)
Telmisartan(Unsafe)
Isradipine(Low Risk)
Sotalol(Low Risk)
Prazosin(Unsafe)
Chlorthalidone(Dangerous)
Verapamil(Safe)
Indapamide(Low Risk)
Losartan(Low Risk)
Captopril(Safe)
Trandolapril(Dangerous)
Irbesartan(Unsafe)
Bumetanide(Low Risk)
Torsemide(Low Risk)
Nadolol(Unsafe)
Reserpine(Unsafe)
Furosemide(Low Risk)
Doxazosin(Safe)
Eprosartan(Low Risk)
Ramipril(Low Risk)
Fosinopril(Low Risk)
Levobunolol(Low Risk)
Bosentan(Low Risk)
Labetalol(Safe)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Diltiazem(Safe)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Verapamil(Safe)
Cinnarizine(Low Risk)
Nebivolol(Unsafe)
Diltiazem(Safe)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Verapamil(Safe)
Cinnarizine(Low Risk)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Minoxidil(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.