Is Plendil ER Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Plendil ER? Is Plendil ER safe for nursing mother and child? Does Plendil ER extracts into breast milk? Does Plendil ER has any long term or short term side effects on infants? Can Plendil ER influence milk supply or can Plendil ER decrease milk supply in lactating mothers?
Plendil ER lactation summary
- DrLact safety Score for Plendil ER is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Plendil ER may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Plendil ER may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Plendil ER low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Plendil ER We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Plendil ER usage in lactation
At latest update no published data were found on excretion into breast milk. Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount.Its high plasma protein binding capacity makes it highly unlikely a passage into milk. It has been described an increased Prolactin plasma level and gynecomastia after using Plendil ER. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants.
Answer by DrLact: About Plendil ER usage in lactation
Because no information is available on the use of Plendil ER during breastfeeding, an alternate drug may be preferred.
Plendil ER Possible Effects in Breastfeeding
Relevant published informaation was not found as of the revision date.
Alternate Drugs
Sotalol(Low Risk)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Propranolol(Safe)
Eprosartan(Low Risk)
Chlorthalidone(Dangerous)
Verapamil(Safe)
Indapamide(Low Risk)
Chlorothiazide(Safe)
Bosentan(Low Risk)
Nimodipine(Safe)
Captopril(Safe)
Trandolapril(Dangerous)
Hydrochlorothiazide(Safe)
Bumetanide(Low Risk)
Torsemide(Low Risk)
Nadolol(Unsafe)
Spironolactone(Safe)
Hydralazine(Safe)
Metoprolol(Safe)
Nifedipine(Safe)
Bendroflumethiazide(Unsafe)
Reserpine(Unsafe)
Nebivolol(Unsafe)
Furosemide(Low Risk)
Doxazosin(Safe)
Benazepril(Safe)
Ramipril(Low Risk)
Fosinopril(Low Risk)
Levobunolol(Low Risk)
Valsartan(Low Risk)
Labetalol(Safe)
Minoxidil(Safe)
Guanfacine(Low Risk)
Terazosin(Unsafe)
Amlodipine(Low Risk)
Telmisartan(Unsafe)
Felodipine(Low Risk)
Carvedilol(Low Risk)
Methyldopa(Safe)
Prazosin(Unsafe)
Bisoprolol(Low Risk)
Enalapril(Safe)
Lisinopril(Low Risk)
Nitrendipine(Safe)
Losartan(Low Risk)
Atenolol(Unsafe)
Nicardipine(Safe)
Irbesartan(Unsafe)
Acebutolol(Unsafe)
Timolol(Safe)
Diltiazem(Safe)
Verapamil(Safe)
Nimodipine(Safe)
Nifedipine(Safe)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Nitrendipine(Safe)
Cinnarizine(Low Risk)
Nicardipine(Safe)
Diltiazem(Safe)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Nimodipine(Safe)
Sildenafil(Safe)
Nifedipine(Safe)
Hydralazine(Safe)
Nebivolol(Unsafe)
Minoxidil(Safe)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Nitroglycerin(Safe)
Nitrendipine(Safe)
Cinnarizine(Low Risk)
Nicardipine(Safe)
Diltiazem(Safe)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Verapamil(Safe)