Is UNII-OL961R6O2C Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-OL961R6O2C? Is UNII-OL961R6O2C safe for nursing mother and child? Does UNII-OL961R6O2C extracts into breast milk? Does UNII-OL961R6O2C has any long term or short term side effects on infants? Can UNII-OL961R6O2C influence milk supply or can UNII-OL961R6O2C decrease milk supply in lactating mothers?
UNII-OL961R6O2C lactation summary
- DrLact safety Score for UNII-OL961R6O2C is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-OL961R6O2C may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-OL961R6O2C may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-OL961R6O2C low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-OL961R6O2C We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-OL961R6O2C usage in lactation
At latest update no published data were found on excretion into breast milk. Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount.Its high plasma protein binding capacity makes it highly unlikely a passage into milk. It has been described an increased Prolactin plasma level and gynecomastia after using UNII-OL961R6O2C. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants.
Answer by DrLact: About UNII-OL961R6O2C usage in lactation
Because no information is available on the use of UNII-OL961R6O2C during breastfeeding, an alternate drug may be preferred.
UNII-OL961R6O2C Possible Effects in Breastfeeding
Relevant published informaation was not found as of the revision date.
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Nicardipine(Safe)
Diltiazem(Safe)
Isradipine(Low Risk)
Nisoldipine(Low Risk)
Verapamil(Safe)
Cinnarizine(Low Risk)
Nimodipine(Safe)
Nifedipine(Safe)
Felodipine(Low Risk)
Amlodipine(Low Risk)
Nitroglycerin(Safe)
Nitrendipine(Safe)
Nebivolol(Unsafe)
Nicardipine(Safe)
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