Is Naloxone Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Naloxone? Is Naloxone safe for nursing mother and child? Does Naloxone extracts into breast milk? Does Naloxone has any long term or short term side effects on infants? Can Naloxone influence milk supply or can Naloxone decrease milk supply in lactating mothers?
Naloxone lactation summary
- DrLact safety Score for Naloxone is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Naloxone may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Naloxone may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Naloxone low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Naloxone We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Naloxone usage in lactation
Antagonist of opium derivative drugs.
Answer by DrLact: About Naloxone usage in lactation
No information is available on the excretion of naloxone into breastmilk. Because it is not orally bioavailable, it is unlikely to affect the breastfed infant. However, if naloxone is required by the mother for an opiate overdose, she should withhold nursing until the opiate is out of her system.
Naloxone Possible Effects in Breastfeeding
In contrast to its effect in some animal species, naloxone does not affect suckling-induced secretion of oxytocin or prolactin in postpartum women.[1][2]