Question

I am a breastfeeding mother and i want to know if it is safe to use Propantheline? Is Propantheline safe for nursing mother and child? Does Propantheline extracts into breast milk? Does Propantheline has any long term or short term side effects on infants? Can Propantheline influence milk supply or can Propantheline decrease milk supply in lactating mothers?

Answer by DrLact: About Propantheline usage in lactation

No information is available on the use of propantheline during breastfeeding. Because propantheline is a quaternary ammonium compound, it is not likely to be absorbed and reach the bloodstream of the infant. Long-term use of propantheline might reduce milk production or milk letdown. During long-term use, observe for signs of decreased lactation (e.g., insatiety, poor weight gain).

Propantheline Possible Effects in Breastfeeding

Relevant published information in nursing mothers was not found as of the revision date. Anticholinergics can inhibit lactation in animals, apparently by inhibiting growth hormone and oxytocin secretion.[1][2][3][4][5] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

Alternate Drugs

Cimetidine(Low Risk)
Senna(Safe)
Doxylamine(Unsafe)
Cimetidine(Low Risk)
Alosetron(Low Risk)
Docusate(Safe)
Dimenhydrinate(Low Risk)
Rifaximin(Safe)
Cascara Sagrada(Low Risk)
Droperidol(Low Risk)
Bisacodyl(Safe)
Cisapride(Safe)
Ursodiol(Safe)
Cyclizine(Low Risk)
Scopolamine(Low Risk)
Tropicamide(Low Risk)
Cyclopentolate(Low Risk)
Tolterodine(Low Risk)
Solifenacin(Unsafe)
Atropine(Safe)
Dicyclomine(Unsafe)
Flavoxate(Low Risk)
Oxybutinyn(Low Risk)
Fesoterodine(Low Risk)
Scopolamine(Low Risk)
Tropicamide(Low Risk)
Cyclopentolate(Low Risk)
Tolterodine(Low Risk)
Solifenacin(Unsafe)
Atropine(Safe)
Dicyclomine(Unsafe)
Flavoxate(Low Risk)
Oxybutinyn(Low Risk)
Fesoterodine(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.