Is Solifenacin Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Solifenacin? Is Solifenacin safe for nursing mother and child? Does Solifenacin extracts into breast milk? Does Solifenacin has any long term or short term side effects on infants? Can Solifenacin influence milk supply or can Solifenacin decrease milk supply in lactating mothers?

• DrLact safety Score for Solifenacin is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of Solifenacin may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that Solifenacin may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using Solifenacin .
• It is recommended to evaluate the advantage of not breastfeeding while using Solifenacin Vs not using Solifenacin And continue breastfeeding.
• While using Solifenacin Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Advice to take a minimal dose for a short time since anti-cholinergic drugs may decrease breast milk production. Check-up for anti-cholinergic symptoms (mouth dryness, constipation...)

Because there is no published experience with solifenacin during breastfeeding and it has a long half-life averaging 55 hours, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. Long-term use of solifenacin might reduce milk production or milk letdown. During long-term use, observe the infant for signs of decreased milk production (e.g., insatiety, poor weight gain) and for anticholinergic symptoms (e.g., constipation, urinary retention, UTI, dry mouth).

Relevant published information in nursing mothers was not found as of the revision date. Anticholinergics can inhibit lactation in animals apparently by inhibiting growth hormone and oxytocin secretion.[1][2][3][4][5] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.