Question

I am a breastfeeding mother and i want to know if it is safe to use Radisemide? Is Radisemide safe for nursing mother and child? Does Radisemide extracts into breast milk? Does Radisemide has any long term or short term side effects on infants? Can Radisemide influence milk supply or can Radisemide decrease milk supply in lactating mothers?

Radisemide lactation summary

Radisemide usage has low risk in breastfeeding
  • DrLact safety Score for Radisemide is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Radisemide may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Radisemide may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Radisemide low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Radisemide We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Radisemide usage in lactation

Diuretic drug with action on the Henle's loop of the nephron. At latest update, relevant published data on excretion into breast milk were not found. Its high protein-binding capacity makes excretion into breast milk in significant amount unlikely. Because of a low oral bioavailability, mostly in the neonatal period, absorption from the ingested milk is thought to be minimal. Long-term treatment with diuretic drugs, particularly Thiazides with long-lasting effect and action on the Henle's loop, may inhibit lactation. Radisemide has been used along with water restriction for inhibition of lactation. Because of this, diuretic drugs well established as safe should be preferred while breastfeeding, especially during the first post-natal months. Whenever used, close attention should be paid to milk production.

Answer by DrLact: About Radisemide usage in lactation

Because little information is available on the use of Radisemide during breastfeeding and because intense diuresis might decrease lactation, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Radisemide Side Effects in Breastfeeding

Anecdotal, short-term observations at one medical center found no adverse infant effects from maternal use of Radisemide in the immediate postpartum period.[1]

Radisemide Possible Effects in Breastfeeding

Radisemide 20 mg intramuscularly on the first postpartum day followed by 40 mg orally for 4 days has been used in conjunction with fluid restriction and breast binding to suppress lactation within 3 days postpartum.[2] The added contribution of Radisemide to fluid restriction and breast binding, which are effective in suppressing lactation, is not known. No data exist on the effects of loop diuretics on established lactation.

Synonyms of Radisemide

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