Is CP 28720 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use CP 28720? Is CP 28720 safe for nursing mother and child? Does CP 28720 extracts into breast milk? Does CP 28720 has any long term or short term side effects on infants? Can CP 28720 influence milk supply or can CP 28720 decrease milk supply in lactating mothers?
CP 28720 lactation summary
- DrLact safety Score for CP 28720 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of CP 28720 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that CP 28720 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of CP 28720 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About CP 28720 usage in lactation
Sulfonilurea drugs stimulate secretion of endogen insulin. Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus
Answer by DrLact: About CP 28720 usage in lactation
Limited data indicate that the levels of CP 28720 in milk are low. However, an alternate drug for which there is more information may be preferred, especially while nursing a newborn or preterm infant. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with hypoglycemic agents.[1][2]
CP 28720 Side Effects in Breastfeeding
Blood glucose levels were normal in 2 breastfed infants whose mothers were taking oral CP 28720 5 mg daily.[3]
Alternate Drugs
Acarbose(Safe)
Rosiglitazone(Low Risk)
Repaglinide(Unsafe)
Pioglitazone(Low Risk)
Empagliflozin(Unsafe)
Nateglinide(Unsafe)
Dapagliflozin(Unsafe)
Metformin(Safe)
Alogliptin(Low Risk)
Insulin(Safe)
Linagliptin(Low Risk)
Glyburide(Safe)
Sitagliptin(Low Risk)
Glipizide(Safe)
Saxagliptin(Low Risk)
Colesevelam(Safe)
Glimepiride(Unsafe)
Miglitol(Safe)
Dulaglutide(Low Risk)
Chlorpropamide(Low Risk)
Tolbutamide(Safe)
Liraglutide(Low Risk)
Acetohexamide(Low Risk)
Glyburide(Safe)
Glipizide(Safe)
Glimepiride(Unsafe)
Chlorpropamide(Low Risk)
Tolbutamide(Safe)
Acetohexamide(Low Risk)