Is Atovaquone Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Atovaquone? Is Atovaquone safe for nursing mother and child? Does Atovaquone extracts into breast milk? Does Atovaquone has any long term or short term side effects on infants? Can Atovaquone influence milk supply or can Atovaquone decrease milk supply in lactating mothers?
Atovaquone lactation summary
- DrLact safety Score for Atovaquone is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Atovaquone may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Atovaquone may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Atovaquone low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Atovaquone We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Atovaquone usage in lactation
Drug used for treatment and prophylaxis of Pneumoystis pneumonia. Also used in combination with Proguanil for treatment of malaria. On latest update relevant data on breastfeeding was not found. Pharmacokinetic data indicates that drug excretion into breast milk would not be significant. It has been approved to treat infants over 5 kg of body weight. May be used in nursing mothers of newborn and babies under 5 kg of body weight since benefit is greater than risk.
Answer by DrLact: About Atovaquone usage in lactation
No information is available on the use of atovaquone during breastfeeding. However, the quantity of drug in breast milk is assumed too low to provide adequate protection against malaria for the breastfed infant.[1] A dosage has been established for infants weighing as little as 5 kg, so it is unlikely to adversely affect breastfed infants weighing 5 kg or more.
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