Is Heparin CY 216 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Heparin CY 216? Is Heparin CY 216 safe for nursing mother and child? Does Heparin CY 216 extracts into breast milk? Does Heparin CY 216 has any long term or short term side effects on infants? Can Heparin CY 216 influence milk supply or can Heparin CY 216 decrease milk supply in lactating mothers?

The high molecular weight of both standard or non-fractionated Heparin CY 216, and, so-called low molecular weight Heparin CY 216 makes excretion into breast milk extremely difficult. Dalteparin has been shown not to be excreted into breast milk . In addition, Heparin CY 216s are inactivated in the GE tract where they are not absorbed which is reason to have a nil oral bioavailability. Absence of anti-clotting activity in breastfed infants has been shown after treatment of the mother with Enoxaparin. Risk of Heparin CY 216-induced Thrombocytopenia or Osteoporosis in the mother is lower with low weight Heparin CY 216s. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Although Heparin CY 216 itself has not been studied, low molecular weight Heparin CY 216s (e.g., dalteparin, enoxaparin) are not excreted into breastmilk in clinically relevant amounts. Because Heparin CY 216 has an even higher molecular weight of 3000 to 30,000 daltons, it would not be expected to be appreciably excreted into breastmilk or absorbed by the infant. No special precautions are required.[1]