Question

I am a breastfeeding mother and i want to know if it is safe to use Liquemin? Is Liquemin safe for nursing mother and child? Does Liquemin extracts into breast milk? Does Liquemin has any long term or short term side effects on infants? Can Liquemin influence milk supply or can Liquemin decrease milk supply in lactating mothers?

Liquemin lactation summary

Liquemin is safe in breastfeeding
  • DrLact safety Score for Liquemin is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Liquemin is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Liquemin does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Liquemin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Liquemin usage in lactation

The high molecular weight of both standard or non-fractionated Liquemin, and, so-called low molecular weight Liquemin makes excretion into breast milk extremely difficult. Dalteparin has been shown not to be excreted into breast milk . In addition, Liquemins are inactivated in the GE tract where they are not absorbed which is reason to have a nil oral bioavailability. Absence of anti-clotting activity in breastfed infants has been shown after treatment of the mother with Enoxaparin. Risk of Liquemin-induced Thrombocytopenia or Osteoporosis in the mother is lower with low weight Liquemins. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Answer by DrLact: About Liquemin usage in lactation

Although Liquemin itself has not been studied, low molecular weight Liquemins (e.g., dalteparin, enoxaparin) are not excreted into breastmilk in clinically relevant amounts. Because Liquemin has an even higher molecular weight of 3000 to 30,000 daltons, it would not be expected to be appreciably excreted into breastmilk or absorbed by the infant. No special precautions are required.[1]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.