Is Sandoparin Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use Sandoparin? Is Sandoparin safe for nursing mother and child? Does Sandoparin extracts into breast milk? Does Sandoparin has any long term or short term side effects on infants? Can Sandoparin influence milk supply or can Sandoparin decrease milk supply in lactating mothers?

Sandoparin lactation summary

DrLact safety Score for Sandoparin is 1 out of 8 which is considered Safe as per our analyses.
A safety Score of 1 indicates that usage of Sandoparin is mostly safe during lactation for breastfed baby.
Our study of different scientific research also indicates that Sandoparin does not cause any serious side effects in breastfeeding mothers.
Most of scientific studies and research papers declaring usage of Sandoparin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Sandoparin usage in lactation

The high molecular weight of both standard or non-fractionated Sandoparin, and, so-called low molecular weight Sandoparin makes excretion into breast milk extremely difficult. Dalteparin has been shown not to be excreted into breast milk . In addition, Sandoparins are inactivated in the GE tract where they are not absorbed which is reason to have a nil oral bioavailability. Absence of anti-clotting activity in breastfed infants has been shown after treatment of the mother with Enoxaparin. Risk of Sandoparin-induced Thrombocytopenia or Osteoporosis in the mother is lower with low weight Sandoparins. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Answer by DrLact: About Sandoparin usage in lactation

Although Sandoparin itself has not been studied, low molecular weight Sandoparins (e.g., dalteparin, enoxaparin) are not excreted into breastmilk in clinically relevant amounts. Because Sandoparin has an even higher molecular weight of 3000 to 30,000 daltons, it would not be expected to be appreciably excreted into breastmilk or absorbed by the infant. No special precautions are required.[1]