Question

I am a breastfeeding mother and i want to know if it is safe to use Bemiparin? Is Bemiparin safe for nursing mother and child? Does Bemiparin extracts into breast milk? Does Bemiparin has any long term or short term side effects on infants? Can Bemiparin influence milk supply or can Bemiparin decrease milk supply in lactating mothers?

Bemiparin lactation summary

Bemiparin is safe in breastfeeding
  • DrLact safety Score for Bemiparin is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Bemiparin is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Bemiparin does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Bemiparin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Bemiparin usage in lactation

The high molecular weight of both standard or non-fractionated Bemiparin, and, so-called low molecular weight Bemiparin makes excretion into breast milk extremely difficult. Dalteparin has been shown not to be excreted into breast milk . In addition, Bemiparins are inactivated in the GE tract where they are not absorbed which is reason to have a nil oral bioavailability. Absence of anti-clotting activity in breastfed infants has been shown after treatment of the mother with Enoxaparin. Risk of Bemiparin-induced Thrombocytopenia or Osteoporosis in the mother is lower with low weight Bemiparins. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Answer by DrLact: About Bemiparin usage in lactation

Although Bemiparin itself has not been studied, low molecular weight Bemiparins (e.g., dalteparin, enoxaparin) are not excreted into breastmilk in clinically relevant amounts. Because Bemiparin has an even higher molecular weight of 3000 to 30,000 daltons, it would not be expected to be appreciably excreted into breastmilk or absorbed by the infant. No special precautions are required.[1]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.