Is Certoparin Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use Certoparin? Is Certoparin safe for nursing mother and child? Does Certoparin extracts into breast milk? Does Certoparin has any long term or short term side effects on infants? Can Certoparin influence milk supply or can Certoparin decrease milk supply in lactating mothers?

Certoparin lactation summary

DrLact safety Score for Certoparin is 1 out of 8 which is considered Safe as per our analyses.
A safety Score of 1 indicates that usage of Certoparin is mostly safe during lactation for breastfed baby.
Our study of different scientific research also indicates that Certoparin does not cause any serious side effects in breastfeeding mothers.
Most of scientific studies and research papers declaring usage of Certoparin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Certoparin usage in lactation

The high molecular weight of both standard or non-fractionated Certoparin, and, so-called low molecular weight Certoparin makes excretion into breast milk extremely difficult. Dalteparin has been shown not to be excreted into breast milk . In addition, Certoparins are inactivated in the GE tract where they are not absorbed which is reason to have a nil oral bioavailability. Absence of anti-clotting activity in breastfed infants has been shown after treatment of the mother with Enoxaparin. Risk of Certoparin-induced Thrombocytopenia or Osteoporosis in the mother is lower with low weight Certoparins. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Answer by DrLact: About Certoparin usage in lactation

Although Certoparin itself has not been studied, low molecular weight Certoparins (e.g., dalteparin, enoxaparin) are not excreted into breastmilk in clinically relevant amounts. Because Certoparin has an even higher molecular weight of 3000 to 30,000 daltons, it would not be expected to be appreciably excreted into breastmilk or absorbed by the infant. No special precautions are required.[1]