Question

I am a breastfeeding mother and i want to know if it is safe to use Amikacin? Is Amikacin safe for nursing mother and child? Does Amikacin extracts into breast milk? Does Amikacin has any long term or short term side effects on infants? Can Amikacin influence milk supply or can Amikacin decrease milk supply in lactating mothers?

Amikacin lactation summary

Amikacin is safe in breastfeeding
  • DrLact safety Score for Amikacin is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Amikacin is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Amikacin does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Amikacin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Amikacin usage in lactation

Levels in the mother's milk are very low and in most instances undetectable. Like other aminoglycosides it is poorly absorbed in the intestine. Large doses may affect intestinal flora. Be aware of false negative bacterial cultures in the infant when the mother is on antibiotics. .

Answer by DrLact: About Amikacin usage in lactation

Amikacin is poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of other aminoglycosides, but serum levels with typical three times daily dosages are far below those attained when treating newborn infections and systemic effects of amikacin are unlikely. Older infants would be expected to absorb even less amikacin. Because there is little variability in the milk amikacin levels during multiple daily dose regimens, timing breastfeeding with respect to the dose is of little or no benefit in reducing infant exposure. Data are not available with single daily dose regimens. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis.

Alternate Drugs

Neomycin(Safe)
Amikacin(Safe)
Kanamycin(Safe)
Naftifine(Safe)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Abacavir(Safe)
Cefoxitin(Safe)
Nevirapine(Low Risk)
Meropenem(Safe)
Dapsone(Low Risk)
Nelfinavir(Unsafe)
Famciclovir(Low Risk)
Enoxacin(Low Risk)
Cefotetan(Safe)
Capreomycin(Low Risk)
Rifaximin(Safe)
Neomycin(Safe)
Cefaclor(Safe)
Erythromycin(Low Risk)
Doxycycline(Low Risk)
Lomefloxacin(Low Risk)
Ertapenem(Safe)
Indinavir(Unsafe)
Zidovudine(Low Risk)
Clindamycin(Low Risk)
Amantadine(Low Risk)
Levofloxacin(Low Risk)
Amikacin(Safe)
Nafcillin(Safe)
Econazole(Safe)
Tenofovir(Safe)
Valganciclovir(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Acyclovir(Safe)
Ganciclovir(Low Risk)
Lindane(Unsafe)
Quinine(Safe)
Cefepime(Safe)
Primaquine(Low Risk)
Efavirenz(Unsafe)
Saquinavir(Unsafe)
Aztreonam(Safe)
Atovaquone(Low Risk)
Didanosine(Unsafe)
Cefprozil(Safe)
Linezolid(Low Risk)
Methicillin(Low Risk)
Ofloxacin(Safe)
Cefdinir(Safe)
Malathion(Low Risk)
Ritonavir(Unsafe)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Mupirocin(Safe)
Enoxacin(Low Risk)
Cefotetan(Safe)
Capreomycin(Low Risk)
Neomycin(Safe)
Cefaclor(Safe)
Erythromycin(Low Risk)
Doxycycline(Low Risk)
Lomefloxacin(Low Risk)
Ertapenem(Safe)
Iodine(Unsafe)
Nalidixic Acid(Low Risk)
Clindamycin(Low Risk)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Demeclocycline(Low Risk)
Cefixime(Safe)
Amikacin(Safe)
Moxifloxacin(Low Risk)
Kanamycin(Safe)
Cefepime(Safe)
Aztreonam(Safe)
Cefprozil(Safe)
Methicillin(Low Risk)
Ofloxacin(Safe)
Cefdinir(Safe)
Methenamine(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.