Question

I am a breastfeeding mother and i want to know if it is safe to use Demeclocycline? Is Demeclocycline safe for nursing mother and child? Does Demeclocycline extracts into breast milk? Does Demeclocycline has any long term or short term side effects on infants? Can Demeclocycline influence milk supply or can Demeclocycline decrease milk supply in lactating mothers?

Demeclocycline lactation summary

Demeclocycline usage has low risk in breastfeeding
  • DrLact safety Score for Demeclocycline is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Demeclocycline may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Demeclocycline may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Demeclocycline low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Demeclocycline We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Demeclocycline usage in lactation

Although it is secreted into breast milk it has not been detected in infant’s blood because it forms unabsorbable chelate compounds with milk calcium. It is not recommended a long-term use (more than 3-4 weeks) since damage on bone growth plates, teeth discoloration, or alteration of intestinal flora may occur. Be aware of the possibility of false negative results of bacterial cultures when the mother is on antibiotics. Withdrawn from the market in Spain.

Answer by DrLact: About Demeclocycline usage in lactation

A number of reviews have stated that tetracyclines are contraindicated during breastfeeding because of possible staining of infants' dental enamel or bone deposition of tetracyclines. However, a close examination of available literature indicates that there is not likely to be harm in short-term use of demeclocycline during lactation because milk levels are low and absorption by the infant is inhibited by the calcium in breastmilk. Short-term use of demeclocycline is acceptable in nursing mothers. As a theoretical precaution, avoid prolonged or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).

Alternate Drugs

Capreomycin(Low Risk)
Rifaximin(Safe)
Famciclovir(Low Risk)
Cefotetan(Safe)
Ertapenem(Safe)
Neomycin(Safe)
Doxycycline(Low Risk)
Indinavir(Unsafe)
Lomefloxacin(Low Risk)
Zidovudine(Low Risk)
Cefaclor(Safe)
Erythromycin(Low Risk)
Amikacin(Safe)
Levofloxacin(Low Risk)
Tenofovir(Safe)
Nafcillin(Safe)
Clindamycin(Low Risk)
Amantadine(Low Risk)
Valganciclovir(Low Risk)
Econazole(Safe)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Ganciclovir(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Lindane(Unsafe)
Saquinavir(Unsafe)
Acyclovir(Safe)
Primaquine(Low Risk)
Quinine(Safe)
Atovaquone(Low Risk)
Cefepime(Safe)
Linezolid(Low Risk)
Efavirenz(Unsafe)
Malathion(Low Risk)
Cefprozil(Safe)
Aztreonam(Safe)
Didanosine(Unsafe)
Ritonavir(Unsafe)
Methicillin(Low Risk)
Ofloxacin(Safe)
Cefdinir(Safe)
Gatifloxacin(Low Risk)
Nevirapine(Low Risk)
Dapsone(Low Risk)
Cefoxitin(Safe)
Nelfinavir(Unsafe)
Meropenem(Safe)
Naftifine(Safe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Abacavir(Safe)
Mupirocin(Safe)
Cefotetan(Safe)
Ertapenem(Safe)
Neomycin(Safe)
Doxycycline(Low Risk)
Lomefloxacin(Low Risk)
Cefaclor(Safe)
Erythromycin(Low Risk)
Nalidixic Acid(Low Risk)
Iodine(Unsafe)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Clindamycin(Low Risk)
Amikacin(Safe)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Cefepime(Safe)
Cefprozil(Safe)
Aztreonam(Safe)
Methicillin(Low Risk)
Ofloxacin(Safe)
Cefdinir(Safe)
Gatifloxacin(Low Risk)
Methenamine(Unsafe)
Cefoxitin(Safe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Capreomycin(Low Risk)
Doxycycline(Low Risk)
Demeclocycline(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.