Question

I am a breastfeeding mother and i want to know if it is safe to use Unazid? Is Unazid safe for nursing mother and child? Does Unazid extracts into breast milk? Does Unazid has any long term or short term side effects on infants? Can Unazid influence milk supply or can Unazid decrease milk supply in lactating mothers?

Unazid lactation summary

Unazid is safe in breastfeeding
  • DrLact safety Score for Unazid is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Unazid is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Unazid does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Unazid safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Unazid usage in lactation

Thiazide diuretic drug. Excretion into breast milk is clinically non-significant. No side-effects were observed in a one-month old breastfed baby whose mother was treated with this medication. Drug level in the plasma of this child was undetectable. Long-term treatment with diuretic drugs (particularly Thiazide type ones with long-lasting effect and loop-acting mechanism) may inhibit lactation, mostly if lactation is not well-established yet. Use as lower dose as possible, especially during the first postnatal month. American Academy of Pediatrics 2013: Maternal Medication Usually Compatible With Breastfeeding. WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Answer by DrLact: About Unazid usage in lactation

Unazid doses of 50 mg daily or less are acceptable during lactation. Intense diuresis with large doses may decrease breastmilk production.

Unazid Side Effects in Breastfeeding

No electrolyte abnormalities were noted in one 28-day-old infant who was breastfed since birth while his mother was taking oral Unazid 50 mg daily.[1]

Unazid Possible Effects in Breastfeeding

Unazid in dosages of 100 mg daily in the morning and 50 mg in the afternoon or 50 mg twice daily have been used to successfully to suppress lactation at various times postpartum.[2][3] Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation.[2][4][5] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.

Synonyms of Unazid

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