I am a breastfeeding mother and i want to know if it is safe to use Desloratadine? Is Desloratadine safe for nursing mother and child? Does Desloratadine extracts into breast milk? Does Desloratadine has any long term or short term side effects on infants? Can Desloratadine influence milk supply or can Desloratadine decrease milk supply in lactating mothers?
- DrLact safety Score for Desloratadine is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Desloratadine is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Desloratadine does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Desloratadine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Second generation anti-histaminic and piperidine drug with mild sedative effect. Active metabolite of loratadine. Loratadine is excreted in non-significant amount into breast milk. No side effects were observed in breastfed infants of treated mothers. The British Society of Immunology and Allergy rates it compatible with breastfeeding. The American Academy of Pediatrics rates it compatible with breastfeeding.
Because of its expected low milk levels and lack of sedation and anticholinergic effects, maternal use of desloratadine is unlikely to affect a breastfed infant or milk production. Desloratadine might have a negative effect on lactation in combination with a sympathomimetic agent such as pseudoephedrine.
Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in nonlactating women and in early postpartum women. However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment of postpartum mothers. Whether lower oral doses of antihistamines have the same effect on serum prolactin or whether the effects on prolactin have any consequences on breastfeeding success have not been studied. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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