Question

I am a breastfeeding mother and i want to know if it is safe to use Physostigmine? Is Physostigmine safe for nursing mother and child? Does Physostigmine extracts into breast milk? Does Physostigmine has any long term or short term side effects on infants? Can Physostigmine influence milk supply or can Physostigmine decrease milk supply in lactating mothers?

Answer by DrLact: About Physostigmine usage in lactation

No information is available on the use of physostigmine during breastfeeding.

Physostigmine Possible Effects in Breastfeeding

Relevant published information in nursing mothers was not found as of the revision date. In animals, cholinergic drugs increase oxytocin release,[2] and have variable effects on serum prolactin.[3] Physostigmine increases serum prolactin in humans.[4][5] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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