Question

I am a breastfeeding mother and i want to know if it is safe to use Flupenthixol? Is Flupenthixol safe for nursing mother and child? Does Flupenthixol extracts into breast milk? Does Flupenthixol has any long term or short term side effects on infants? Can Flupenthixol influence milk supply or can Flupenthixol decrease milk supply in lactating mothers?

Flupenthixol lactation summary

Flupenthixol is safe in breastfeeding
  • DrLact safety Score for Flupenthixol is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Flupenthixol is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Flupenthixol does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Flupenthixol safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Flupenthixol usage in lactation

We are working on a comment for this product.

Answer by DrLact: About Flupenthixol usage in lactation

Flupenthixol is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. Limited information indicates that maternal oral doses of up to 4 mg daily or depot injections of 40 mg every 2 weeks produce low levels in milk and breastfed infants' serum, and cause no adverse developmental consequences. Until more data are available, flupenthixol should be used with careful monitoring during breastfeeding.

Flupenthixol Side Effects in Breastfeeding

A woman took flupenthixol 1 mg and nortriptyline 100 mg daily during pregnancy and flupenthixol 4 mg and nortriptyline 125 mg daily immediately postpartum. She exclusively breastfed her infant. Over a 4-month period, the infant showed no signs of adverse drug effects and had normal motor development with a maternal dosage of flupenthixol 2 mg daily and nortriptyline 75 mg daily.[2]

Flupenthixol Possible Effects in Breastfeeding

Flupenthixol can increase serum prolactin[3][4][5] and has caused galactorrrhea.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.