Is Alemtuzumab Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Alemtuzumab? Is Alemtuzumab safe for nursing mother and child? Does Alemtuzumab extracts into breast milk? Does Alemtuzumab has any long term or short term side effects on infants? Can Alemtuzumab influence milk supply or can Alemtuzumab decrease milk supply in lactating mothers?

IgG-monoclonal antibody that targets leukemic cells receptors. Use for Esclerosis Multiple has been approved. Because a high molecular weight excretion into breast milk is unlikely and destruction of protein structure in infant's bowel renders intestinal absorption nil. It should be avoid in the first two post-partum weeks since pass of significant amounts of IgG to the milk can occur in the first 3 - 4 post-partum days.

No information is available on the clinical use of alemtuzumab during breastfeeding. Because alemtuzumab is a large protein molecule with a molecular weight of 145,454, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, alemtuzumab should be used with caution or avoided during breastfeeding, especially while nursing a newborn or preterm infant.[1][2][3] The manufacturer recommends that breastfeeding be discontinued during alemtuzumab therapy.