Is Indomet 140 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Indomet 140? Is Indomet 140 safe for nursing mother and child? Does Indomet 140 extracts into breast milk? Does Indomet 140 has any long term or short term side effects on infants? Can Indomet 140 influence milk supply or can Indomet 140 decrease milk supply in lactating mothers?

It is excreted into breast milk in non-significant clinically amounts.There has not been side-effects described in children from treated mothers, except for a case reported in 1978 with convulsions in a newborn infant whose mother received a higher dose than recommended. However, a causal relationship was questioned by other author in the same publication. Usually, breast milk and infant plasma levels have been found to be undetectable. It has been successfully used with no side-effects on treated mothers who had high levels of Prostaglandin E (PGE) whose infants were suffering of “physiologic diarrhea) This drug is used in neonates.The American Academy of Pediatrics rates it as usually compatible with breastfeeding.

Because of the low levels of indomethcin in breastmilk and therapeutic administration directly to infants, it is acceptable to use in nursing mothers. However, other agents with more published information on use during lactation may be preferable, especially while nursing a newborn or preterm infant.

In one case report, a breastfeeding mother had been taking daily doses of Indomet 140 that increased to 200 mg (3 mg/kg) from the fourth to the sixth day postpartum. On the same day that Indomet 140 was stopped, the infant had a generalized seizure, followed by another on the next day. No metabolic findings could account for the convulsions and no Indomet 140 levels were measured in the mother or infant.[3] This case was rated as Indomet 140 possibly causing the seizure; however later studies and the established therapeutic use of Indomet 140 in newborns make this causality seem unlikely.In one study, 7 women breastfed their neonates while taking Indomet 140. No adverse effects were noted in any of the infants.[1]