Is Isradipinum Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Isradipinum? Is Isradipinum safe for nursing mother and child? Does Isradipinum extracts into breast milk? Does Isradipinum has any long term or short term side effects on infants? Can Isradipinum influence milk supply or can Isradipinum decrease milk supply in lactating mothers?
Isradipinum lactation summary
- DrLact safety Score for Isradipinum is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Isradipinum may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Isradipinum may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Isradipinum low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Isradipinum We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Isradipinum usage in lactation
At latest update no published data were found on excretion into breast milk. Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount.Its high plasma protein binding capacity makes it highly unlikely a passage into milk.Although it has a low oral bioavailability this may increase by 20% when administered with a meal, which would increase the oral absorption in the infant. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants.
Answer by DrLact: About Isradipinum usage in lactation
Because no information is available on the use of Isradipinum during breastfeeding, an alternate drug may be preferred.
Alternate Drugs
Diltiazem(Safe)
Timolol(Safe)
Terazosin(Unsafe)
Isradipine(Low Risk)
Sotalol(Low Risk)
Nisoldipine(Low Risk)
Telmisartan(Unsafe)
Chlorthalidone(Dangerous)
Verapamil(Safe)
Indapamide(Low Risk)
Propranolol(Safe)
Prazosin(Unsafe)
Chlorothiazide(Safe)
Trandolapril(Dangerous)
Hydrochlorothiazide(Safe)
Nimodipine(Safe)
Losartan(Low Risk)
Captopril(Safe)
Torsemide(Low Risk)
Nadolol(Unsafe)
Irbesartan(Unsafe)
Bumetanide(Low Risk)
Spironolactone(Safe)
Hydralazine(Safe)
Metoprolol(Safe)
Reserpine(Unsafe)
Furosemide(Low Risk)
Nifedipine(Safe)
Bendroflumethiazide(Unsafe)
Ramipril(Low Risk)
Fosinopril(Low Risk)
Levobunolol(Low Risk)
Doxazosin(Safe)
Eprosartan(Low Risk)
Benazepril(Safe)
Bosentan(Low Risk)
Labetalol(Safe)
Minoxidil(Safe)
Guanfacine(Low Risk)
Felodipine(Low Risk)
Carvedilol(Low Risk)
Amlodipine(Low Risk)
Bisoprolol(Low Risk)
Methyldopa(Safe)
Nebivolol(Unsafe)
Enalapril(Safe)
Atenolol(Unsafe)
Lisinopril(Low Risk)
Nitrendipine(Safe)
Valsartan(Low Risk)
Acebutolol(Unsafe)
Nicardipine(Safe)
Isradipine(Low Risk)
Nisoldipine(Low Risk)
Verapamil(Safe)
Cinnarizine(Low Risk)
Nimodipine(Safe)
Nifedipine(Safe)
Felodipine(Low Risk)
Amlodipine(Low Risk)
Nitrendipine(Safe)
Nicardipine(Safe)
Diltiazem(Safe)
Verapamil(Safe)
Cinnarizine(Low Risk)
Nimodipine(Safe)
Hydralazine(Safe)
Nifedipine(Safe)
Felodipine(Low Risk)
Minoxidil(Safe)
Amlodipine(Low Risk)
Sildenafil(Safe)
Nitroglycerin(Safe)
Nebivolol(Unsafe)
Nitrendipine(Safe)
Nicardipine(Safe)
Diltiazem(Safe)
Isradipine(Low Risk)
Nisoldipine(Low Risk)