Question

I am a breastfeeding mother and i want to know if it is safe to use (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid? Is (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid safe for nursing mother and child? Does (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid extracts into breast milk? Does (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid has any long term or short term side effects on infants? Can (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid influence milk supply or can (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid decrease milk supply in lactating mothers?

(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid lactation summary

(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid is safe in breastfeeding
  • DrLact safety Score for (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid usage in lactation

Excretion into breast milk is insignificant and safe for pediatric treatment. Since the possibility of harmful effects on the blood and kidney among treated patients is controversial (not through breast milk) high dosing would better be avoided within 21 days post delivery. Keratolac eye drops are very safe because a low content of drug. The American Academy of Pediatrics rates it usually compatible with breastfeeding.

Answer by DrLact: About (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid usage in lactation

Limited data indicate that milk levels of (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid are low with the usual oral dosage, but milk levels have not been measured after higher injectable dosages. Use caution when using systemic (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid in nursing mothers, especially with the injectable drug. Maternal use of (+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid eye drops would not be expected to cause any adverse effects in breastfed infants. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.