Is Hbw-023 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Hbw-023? Is Hbw-023 safe for nursing mother and child? Does Hbw-023 extracts into breast milk? Does Hbw-023 has any long term or short term side effects on infants? Can Hbw-023 influence milk supply or can Hbw-023 decrease milk supply in lactating mothers?
Hbw-023 lactation summary
- DrLact safety Score for Hbw-023 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Hbw-023 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Hbw-023 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Hbw-023 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Hbw-023 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Hbw-023 usage in lactation
Hirudin is a 65 aminoacid-containing protein that has a direct inhibitory effect on thrombin, which is extracted from leech. Due to a higher molecular weight, excretion to breast milk and absorption are unlikely.
Answer by DrLact: About Hbw-023 usage in lactation
Limited information indicates that Hbw-023 in doses up to 100 mg daily produce very low levels in milk. Because of its large molecular weight, it would not be expected to be absorbed from breastmilk by the infant. Hbw-023 would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months.[1]
Hbw-023 Side Effects in Breastfeeding
One infant was breastfed for 3 months during therapeutic Hbw-023 use beginning at 7 weeks of age. No bleeding events occurred.[2]
Alternate Drugs
Acenocoumarol(Safe)
Warfarin(Safe)
Fondaparinux(Safe)
Lepirudin(Low Risk)
Heparin(Safe)
Enoxaparin(Safe)
Desirudin(Unsafe)
Dalteparin(Safe)
Rivaroxaban(Low Risk)
Abciximab(Low Risk)
Lepirudin(Low Risk)