Is (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate? Is (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate safe for nursing mother and child? Does (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate extracts into breast milk? Does (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate has any long term or short term side effects on infants? Can (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate influence milk supply or can (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate decrease milk supply in lactating mothers?
(S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate lactation summary
- DrLact safety Score for (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate usage in lactation
Higher caution on early neonatal period is required. Check-up for blood hypotension and muscular hypotonia.
Answer by DrLact: About (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate usage in lactation
Because no information is available on the use of (S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Alternate Drugs
Captopril(Safe)
Benazepril(Safe)
Fosinopril(Low Risk)
Trandolapril(Dangerous)
Enalapril(Safe)
Ramipril(Low Risk)
Lisinopril(Low Risk)
Isradipine(Low Risk)
Eprosartan(Low Risk)
Doxazosin(Safe)
Captopril(Safe)
Carvedilol(Low Risk)
Indapamide(Low Risk)
Bumetanide(Low Risk)
Bisoprolol(Low Risk)
Guanfacine(Low Risk)
Hydrochlorothiazide(Safe)
Nitrendipine(Safe)
Bosentan(Low Risk)
Bendroflumethiazide(Unsafe)
Atenolol(Unsafe)
Hydralazine(Safe)
Nicardipine(Safe)
Nisoldipine(Low Risk)
Acebutolol(Unsafe)
Furosemide(Low Risk)
Nimodipine(Safe)
Nebivolol(Unsafe)
Benazepril(Safe)
Verapamil(Safe)
Timolol(Safe)
Nifedipine(Safe)
Amlodipine(Low Risk)
Fosinopril(Low Risk)
Sotalol(Low Risk)
Valsartan(Low Risk)
Felodipine(Low Risk)
Propranolol(Safe)
Terazosin(Unsafe)
Trandolapril(Dangerous)
Minoxidil(Safe)
Telmisartan(Unsafe)
Torsemide(Low Risk)
Prazosin(Unsafe)
Spironolactone(Safe)
Enalapril(Safe)
Nadolol(Unsafe)
Methyldopa(Safe)
Reserpine(Unsafe)
Diltiazem(Safe)
Metoprolol(Safe)
Losartan(Low Risk)
Irbesartan(Unsafe)
Ramipril(Low Risk)
Chlorthalidone(Dangerous)
Levobunolol(Low Risk)
Lisinopril(Low Risk)
Chlorothiazide(Safe)
Labetalol(Safe)