Question

I am a breastfeeding mother and i want to know if it is safe to use KT 3777? Is KT 3777 safe for nursing mother and child? Does KT 3777 extracts into breast milk? Does KT 3777 has any long term or short term side effects on infants? Can KT 3777 influence milk supply or can KT 3777 decrease milk supply in lactating mothers?

KT 3777 lactation summary

KT 3777 is safe in breastfeeding
  • DrLact safety Score for KT 3777 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of KT 3777 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that KT 3777 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of KT 3777 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About KT 3777 usage in lactation

Second-generation cephalosporin for oral administration with a chemical structure similar to cefaclor. At latest update no published data on excretion into breast milk were found. Cephalosporins for which data are available have shown to be excreted into milk in non-significant amount from a therapeutic point of view without reported complications in infants related to them.Cephalosporins are widely used in the Pediatric practice with a high tolerance, even in the neonatal period, so it is very unlikely that such small amounts present in the milk may be a cause of problems to the infant. Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.

Answer by DrLact: About KT 3777 usage in lactation

Although no information is available on the use of KT 3777 during breastfeeding, beta-lactam antibiotics are generally not be expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with beta-lactams, but these effects have not been adequately evaluated. KT 3777 is acceptable in nursing mothers.

Alternate Drugs

Zidovudine(Low Risk)
Moxifloxacin(Low Risk)
Clindamycin(Low Risk)
Cefepime(Safe)
Amantadine(Low Risk)
Econazole(Safe)
Tenofovir(Safe)
Aztreonam(Safe)
Cefprozil(Safe)
Acyclovir(Safe)
Valganciclovir(Low Risk)
Lindane(Unsafe)
Methicillin(Low Risk)
Quinine(Safe)
Ganciclovir(Low Risk)
Cefdinir(Safe)
Saquinavir(Unsafe)
Primaquine(Low Risk)
Efavirenz(Unsafe)
Atovaquone(Low Risk)
Ofloxacin(Safe)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Didanosine(Unsafe)
Cefoxitin(Safe)
Meropenem(Safe)
Linezolid(Low Risk)
Malathion(Low Risk)
Enoxacin(Low Risk)
Cefotetan(Safe)
Ritonavir(Unsafe)
Naftifine(Safe)
Cefaclor(Safe)
Doxycycline(Low Risk)
Abacavir(Safe)
Nevirapine(Low Risk)
Amikacin(Safe)
Dapsone(Low Risk)
Neomycin(Safe)
Nelfinavir(Unsafe)
Famciclovir(Low Risk)
Lomefloxacin(Low Risk)
Capreomycin(Low Risk)
Rifaximin(Safe)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Erythromycin(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Ertapenem(Safe)
Kanamycin(Safe)
Indinavir(Unsafe)
Cefprozil(Safe)
Aztreonam(Safe)
Methicillin(Low Risk)
Cefdinir(Safe)
Methenamine(Unsafe)
Ofloxacin(Safe)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Enoxacin(Low Risk)
Cefotetan(Safe)
Cefaclor(Safe)
Doxycycline(Low Risk)
Neomycin(Safe)
Mupirocin(Safe)
Lomefloxacin(Low Risk)
Amikacin(Safe)
Capreomycin(Low Risk)
Nalidixic Acid(Low Risk)
Nafcillin(Safe)
Erythromycin(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Levofloxacin(Low Risk)
Ertapenem(Safe)
Iodine(Unsafe)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Clindamycin(Low Risk)
Cefepime(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.