Question

I am a breastfeeding mother and i want to know if it is safe to use 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine? Is 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine safe for nursing mother and child? Does 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine extracts into breast milk? Does 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine has any long term or short term side effects on infants? Can 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine influence milk supply or can 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine decrease milk supply in lactating mothers?

2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine lactation summary

2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine is unsafe in breastfeeding
  • DrLact safety Score for 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine .
  • It is recommended to evaluate the advantage of not breastfeeding while using 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine Vs not using 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine And continue breastfeeding.
  • While using 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine usage in lactation

No data on transfer into breastmilk are available.

Answer by DrLact: About 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine usage in lactation

Because no information is available on the use of 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine Possible Effects in Breastfeeding

2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine can elevate serum prolactin.[2] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[3] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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