Is NSC 186066 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NSC 186066? Is NSC 186066 safe for nursing mother and child? Does NSC 186066 extracts into breast milk? Does NSC 186066 has any long term or short term side effects on infants? Can NSC 186066 influence milk supply or can NSC 186066 decrease milk supply in lactating mothers?
NSC 186066 lactation summary
- DrLact safety Score for NSC 186066 is 5 out of 8 which is considered Unsafe as per our analyses.
- A safety Score of 5 indicates that usage of NSC 186066 may cause serious side effects in breastfed baby.
- Our study of different scientific research indicates that NSC 186066 may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using NSC 186066 .
- It is recommended to evaluate the advantage of not breastfeeding while using NSC 186066 Vs not using NSC 186066 And continue breastfeeding.
- While using NSC 186066 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NSC 186066 usage in lactation
No data on transfer into breastmilk are available. It may lengthen QT interval. Check-up for sedation. Risk of SIDS.
Answer by DrLact: About NSC 186066 usage in lactation
Because there is no published experience with NSC 186066 during breastfeeding, other antipsychotic agents are preferred.
NSC 186066 Possible Effects in Breastfeeding
Phenothiazines cause galactorrhea in 26 to 40% of female patients.[1][2] Hyperprolactinemia appears to be the cause of the galactorrhea.[3][4][5] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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