Question

I am a breastfeeding mother and i want to know if it is safe to use Diuramine? Is Diuramine safe for nursing mother and child? Does Diuramine extracts into breast milk? Does Diuramine has any long term or short term side effects on infants? Can Diuramine influence milk supply or can Diuramine decrease milk supply in lactating mothers?

Diuramine lactation summary

Diuramine is unsafe in breastfeeding
  • DrLact safety Score for Diuramine is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Diuramine may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Diuramine may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Diuramine .
  • It is recommended to evaluate the advantage of not breastfeeding while using Diuramine Vs not using Diuramine And continue breastfeeding.
  • While using Diuramine Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Diuramine usage in lactation

We are working on a comment for this product.

Answer by DrLact: About Diuramine usage in lactation

Both methenamine and mandelic acid pass into milk in small quantities. Diuramine appears acceptable to use, even while nursing a newborn.

Diuramine Side Effects in Breastfeeding

Four newborn infants were allowed to breastfeed in one study after a maternal dose of 1 gram of methenamine hippurate. No adverse effects were reported.[1] Six infants were allowed to nurse during maternal ingestion of the large daily dosage of 12 grams of mandelic acid. There was no clinical or laboratory evidence of harm to the infants.[2]

Alternate Drugs

Nalidixic Acid(Low Risk)
Methenamine(Unsafe)
Aztreonam(Safe)
Cefprozil(Safe)
Neomycin(Safe)
Nalidixic Acid(Low Risk)
Cefoxitin(Safe)
Gatifloxacin(Low Risk)
Cefotetan(Safe)
Enoxacin(Low Risk)
Nafcillin(Safe)
Doxycycline(Low Risk)
Amikacin(Safe)
Moxifloxacin(Low Risk)
Capreomycin(Low Risk)
Ertapenem(Safe)
Cefixime(Safe)
Demeclocycline(Low Risk)
Methicillin(Low Risk)
Cefepime(Safe)
Methenamine(Unsafe)
Cefdinir(Safe)
Iodine(Unsafe)
Cefazolin(Safe)
Mupirocin(Safe)
Cefaclor(Safe)
Ofloxacin(Safe)
Erythromycin(Low Risk)
Lomefloxacin(Low Risk)
Clindamycin(Low Risk)
Levofloxacin(Low Risk)
Kanamycin(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.