Is MK 351 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use MK 351? Is MK 351 safe for nursing mother and child? Does MK 351 extracts into breast milk? Does MK 351 has any long term or short term side effects on infants? Can MK 351 influence milk supply or can MK 351 decrease milk supply in lactating mothers?
MK 351 lactation summary
- DrLact safety Score for MK 351 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of MK 351 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that MK 351 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of MK 351 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About MK 351 usage in lactation
Excreted into breast milk in non-significant amount without side-effects observed in breastfed infants from mothers who were on this medication. Plasma levels in those infants were undetectable or very low. Prolactin level may be increased with the appearance of galactorrhea. Such increase of Prolactin level will not affect breastfeeding ability of a mother who has an established lactation. The American Academy of Pediatrics rates is as compatible with breastfeeding. List of Medicines (WHO-2002): compatible with Breastfeeding.
Answer by DrLact: About MK 351 usage in lactation
Because of the low levels of MK 351 in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants. No special precautions are required.
MK 351 Side Effects in Breastfeeding
No acute or long-term adverse effects were reported in any 15 infants ranging in age from less than 1 week to 8 weeks of age whose mothers were taking MK 351 0.25 to 1.5 g/day orally.[1][2][3][4]
MK 351 Possible Effects in Breastfeeding
MK 351 can increase serum prolactin and has caused galactorrhea.[5][6][7][8] The maternal prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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