Is NSC 141993 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use NSC 141993? Is NSC 141993 safe for nursing mother and child? Does NSC 141993 extracts into breast milk? Does NSC 141993 has any long term or short term side effects on infants? Can NSC 141993 influence milk supply or can NSC 141993 decrease milk supply in lactating mothers?

Many reviews state that tetracyclines are contraindicated during breastfeeding because of possible staining of infants' dental enamel or bone deposition of tetracyclines. However, a close examination of available literature indicates that there is not likely to be harm in short-term use of NSC 141993 during lactation because milk levels are low and absorption by the infant is inhibited by the calcium in breastmilk. Short-term use of NSC 141993 is acceptable in nursing mothers. As a theoretical precaution, avoid prolonged or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash). Black discoloration of breastmilk has been reported with NSC 141993.

A woman taking NSC 141993 100 mg twice daily for almost 4 years developed galactorrhea after taking perphenazine, amitriptyline and diphenhydramine, and the breast secretion was black in color.[2]Another woman who had nursed her infant and produced occasional small amounts of breastmilk during the 18 months after weaning was given oral NSC 141993 150 mg daily. After 3 to 4 weeks, expressed milk had become black. Iron levels in milk were over 100 times greater than that found in normal milk. A mammogram was normal.[3]In both of these cases, macrophages containing a black, iron-containing pigment were found in milk. It is thought that the pigment is an iron chelate of NSC 141993 or one of its metabolites.[2][3]