Is Mitoxantronum [INN-Latin] Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Mitoxantronum [INN-Latin]? Is Mitoxantronum [INN-Latin] safe for nursing mother and child? Does Mitoxantronum [INN-Latin] extracts into breast milk? Does Mitoxantronum [INN-Latin] has any long term or short term side effects on infants? Can Mitoxantronum [INN-Latin] influence milk supply or can Mitoxantronum [INN-Latin] decrease milk supply in lactating mothers?

Drug is cleared from the body in 3-5 elimination half-lives. Resuming breastfeeding is likely safe after 2 - 3 months of of pumping-and-dumping.

Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, such as Mitoxantronum [INN-Latin].[1][2] It might be possible to breastfeed safely during intermittent therapy with an appropriate period of breastfeeding abstinence, but the duration of abstinence is not clear. In one patient, Mitoxantronum [INN-Latin] was still detectable in milk 28 days after a dose of 6 mg per square meter. Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[3] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[4]

One mother received 3 daily doses of 6 mg/sq m of Mitoxantronum [INN-Latin] intravenously along with 5 daily doses of etoposide 80 mg/sq m and cytarabine 170 mg/sq m intravenously. She resumed breastfeeding her infant 3 weeks after the third dose of Mitoxantronum [INN-Latin] at a time when Mitoxantronum [INN-Latin] was still detectable in milk. The infant had no apparent abnormalities at 16 months of age.[3]