Question

I am a breastfeeding mother and i want to know if it is safe to use Treprostinil? Is Treprostinil safe for nursing mother and child? Does Treprostinil extracts into breast milk? Does Treprostinil has any long term or short term side effects on infants? Can Treprostinil influence milk supply or can Treprostinil decrease milk supply in lactating mothers?

Answer by DrLact: About Treprostinil usage in lactation

One patient taking treprostinil breastfed her infant for one year without any complications. If treprostinil is required by the mother, it is not a reason to discontinue breastfeeding. However, until more data are available, treprostinil should only be used with careful monitoring during breastfeeding.

Treprostinil Side Effects in Breastfeeding

A woman developed pulmonary artery hypertension and was treated with intravenous treprostinil beginning at 32 weeks of gestation and titrated up to 26 ng/kg/min. The dose was nearly doubled postpartum because of worsening symptoms. She breastfed (extent not stated) her infant for one year with no apparent drug-related problems, although there was concern for obesity at 6 months of age. The infant was healthy and developing normally at 2 years of age.[1]
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