Is 4-(6-Methoxy-2-naphthyl)-2-butanone Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use 4-(6-Methoxy-2-naphthyl)-2-butanone? Is 4-(6-Methoxy-2-naphthyl)-2-butanone safe for nursing mother and child? Does 4-(6-Methoxy-2-naphthyl)-2-butanone extracts into breast milk? Does 4-(6-Methoxy-2-naphthyl)-2-butanone has any long term or short term side effects on infants? Can 4-(6-Methoxy-2-naphthyl)-2-butanone influence milk supply or can 4-(6-Methoxy-2-naphthyl)-2-butanone decrease milk supply in lactating mothers?

4-(6-Methoxy-2-naphthyl)-2-butanone lactation summary

4-(6-Methoxy-2-naphthyl)-2-butanone usage has low risk in breastfeeding

DrLact safety Score for 4-(6-Methoxy-2-naphthyl)-2-butanone is 3 out of 8 which is considered Low Risk as per our analyses.
A safety Score of 3 indicates that usage of 4-(6-Methoxy-2-naphthyl)-2-butanone may cause some minor side effects in breastfed baby.
Our study of different scientific research indicates that 4-(6-Methoxy-2-naphthyl)-2-butanone may cause moderate to no side effects in lactating mother.
Most of scientific studies and research papers declaring usage of 4-(6-Methoxy-2-naphthyl)-2-butanone low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
While using 4-(6-Methoxy-2-naphthyl)-2-butanone We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 4-(6-Methoxy-2-naphthyl)-2-butanone usage in lactation

Latest update failed to find relevant data on breastfeeding. Both a high molecular weight and high plasma protein-binding makes excretion into breast milk unlikely. The infant is further protected because of a low oral bioavailability. Until more information on this drug concerning breastfeeding is available, a safer alternative should be preferred.

Answer by DrLact: About 4-(6-Methoxy-2-naphthyl)-2-butanone usage in lactation

Because no information is available on the use of 4-(6-Methoxy-2-naphthyl)-2-butanone during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

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