Is 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-? Is 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- safe for nursing mother and child? Does 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- extracts into breast milk? Does 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- has any long term or short term side effects on infants? Can 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- influence milk supply or can 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- decrease milk supply in lactating mothers?
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- lactation summary
- DrLact safety Score for 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- usage in lactation
Not commercially available in SpainBe aware of the possibility of false negative results of bacterial cultures when the mother is on antibiotics.
Answer by DrLact: About 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- usage in lactation
Although no information is available on the use of 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- during breastfeeding, penicillins are generally not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2-ethoxy-1-naphthalenyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))- is acceptable in nursing mothers.
Alternate Drugs
Floxacillin(Safe)
Cefotetan(Safe)
Loracarbef(Safe)
Ampicillin(Safe)
Cefuroxime(Safe)
Lindane(Unsafe)
Neomycin(Safe)
Cefadroxil(Safe)
Acyclovir(Safe)
Valganciclovir(Low Risk)
Doxycycline(Low Risk)
Penicillin V(Safe)
Emtricitabine(Safe)
Tetracycline(Safe)
Permethrin(Safe)
Quinine(Safe)
Ganciclovir(Low Risk)
Tioconazole(Safe)
Cefotaxime(Safe)
Sulfamethoxazole(Safe)
Efavirenz(Unsafe)
Lomefloxacin(Low Risk)
Ceftriaxone(Safe)
Praziquantel(Safe)
Saquinavir(Unsafe)
Cefaclor(Safe)
Pyrimethamine(Safe)
Terconazole(Safe)
Primaquine(Low Risk)
Didanosine(Unsafe)
Streptomycin(Safe)
Mefloquine(Safe)
Secnidazole(Safe)
Dicloxacillin(Safe)
Sulconazole(Safe)
Penicillin G(Safe)
Atovaquone(Low Risk)
Sulfisoxazole(Safe)
Levofloxacin(Low Risk)
Salicylic Acid(Safe)
Mebendazole(Safe)
Nafcillin(Safe)
Hydroxychloroquine(Safe)
Teicoplanin(Safe)
Linezolid(Low Risk)
Malathion(Low Risk)
Ritonavir(Unsafe)
Chloroquine(Safe)
Demeclocycline(Low Risk)
Polymyxin B(Safe)
Cefixime(Safe)
Kanamycin(Safe)
Amoxicillin(Safe)
Ceftibuten(Safe)
Moxifloxacin(Low Risk)
Fusidic Acid(Safe)
Oxiconazole(Safe)
Oxytetracycline(Safe)
Vancomycin(Safe)
Abacavir(Safe)
Colistimethate(Safe)
Nevirapine(Low Risk)
Trovafloxacin(Unsafe)
Naftifine(Safe)
Cefepime(Safe)
Oseltamivir(Safe)
Procaine Penicillin G(Safe)
Ceftazidime(Safe)
Nelfinavir(Unsafe)
Paromomycin(Safe)
Cloxacillin(Safe)
Dapsone(Low Risk)
Penciclovir(Safe)
Tinidazole(Safe)
Tobramycin(Safe)
Ciclopirox(Safe)
Famciclovir(Low Risk)
Chloramphenicol(Unsafe)
Amikacin(Safe)
Nitazoxanide(Safe)
Cefprozil(Safe)
Sulfasalazine(Safe)
Ciprofloxacin(Safe)
Butoconazole(Safe)
Capreomycin(Low Risk)
Roxithromycin(Safe)
Gentamicin(Safe)
Piperacillin(Safe)
Rifaximin(Safe)
Lamivudine(Safe)
Methicillin(Low Risk)
Bacampicillin(Safe)
Ofloxacin(Safe)
Erythromycin(Low Risk)
Indinavir(Unsafe)
Ticarcillin(Safe)
Cephradine(Safe)
Albendazole(Safe)
Ertapenem(Safe)
Cefdinir(Safe)
Gatifloxacin(Low Risk)
Metronidazole(Safe)
Aztreonam(Safe)
Zidovudine(Low Risk)
Norfloxacin(Safe)
Clindamycin(Low Risk)
Econazole(Safe)
Cefoxitin(Safe)
Amantadine(Low Risk)
Meropenem(Safe)
Cephalexin(Safe)
Cefazolin(Safe)
Clarithromycin(Safe)
Enoxacin(Low Risk)
Telithromycin(Unsafe)
Ivermectin(Safe)
Tenofovir(Safe)
Azithromycin(Safe)
Penicillin V(Safe)
Tetracycline(Safe)
Cefotaxime(Safe)
Sulfamethoxazole(Safe)
Lomefloxacin(Low Risk)
Ceftriaxone(Safe)
Nalidixic Acid(Low Risk)
Cefaclor(Safe)
Streptomycin(Safe)
Dicloxacillin(Safe)
Penicillin G(Safe)
Sulfisoxazole(Safe)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Demeclocycline(Low Risk)
Polymyxin B(Safe)
Cefixime(Safe)
Trimethoprim(Safe)
Kanamycin(Safe)
Amoxicillin(Safe)
Ceftibuten(Safe)
Fosfomycin(Safe)
Moxifloxacin(Low Risk)
Teicoplanin(Safe)
Oxytetracycline(Safe)
Vancomycin(Safe)
Colistimethate(Safe)
Trovafloxacin(Unsafe)
Cefepime(Safe)
Procaine Penicillin G(Safe)
Ceftazidime(Safe)
Fusidic Acid(Safe)
Cloxacillin(Safe)
Tinidazole(Safe)
Tobramycin(Safe)
Mupirocin(Safe)
Chloramphenicol(Unsafe)
Cefprozil(Safe)
Ciprofloxacin(Safe)
Capreomycin(Low Risk)
Gentamicin(Safe)
Piperacillin(Safe)
Methicillin(Low Risk)
Bacampicillin(Safe)
Ofloxacin(Safe)
Erythromycin(Low Risk)
Iodine(Unsafe)
Amikacin(Safe)
Sulfasalazine(Safe)
Ticarcillin(Safe)
Cephradine(Safe)
Ertapenem(Safe)
Cefdinir(Safe)
Gatifloxacin(Low Risk)
Metronidazole(Safe)
Methenamine(Unsafe)
Aztreonam(Safe)
Norfloxacin(Safe)
Clindamycin(Low Risk)
Enoxacin(Low Risk)
Cefoxitin(Safe)
Methenamine Mandelate(Unsafe)
Cephalexin(Safe)
Cefazolin(Safe)
Chlorhexidine(Safe)
Nitrofurantoin(Safe)
Floxacillin(Safe)
Cefotetan(Safe)
Loracarbef(Safe)
Ampicillin(Safe)
Cefuroxime(Safe)
Neomycin(Safe)
Cefadroxil(Safe)
Doxycycline(Low Risk)
Dicloxacillin(Safe)
Penicillin G(Safe)
Nafcillin(Safe)
Amoxicillin(Safe)
Procaine Penicillin G(Safe)
Cloxacillin(Safe)
Piperacillin(Safe)
Methicillin(Low Risk)
Bacampicillin(Safe)
Ticarcillin(Safe)
Floxacillin(Safe)
Ampicillin(Safe)
Penicillin V(Safe)