Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg.
What is Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg used for?
LEXXEL is indicated for the treatment of hypertension.This fixed combination drug is not indicated for the initial therapy of hypertension. (See DOSAGE AND ADMINISTRATION.)In using LEXXEL, consideration should be given to the fact that another angiotensin converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease, and that available data are insufficient to show that enalapril (a component of LEXXEL) does not have a similar risk. (See WARNINGS, Neutropenia/Agranulocytosis.)In considering use of LEXXEL, it should be noted that black patients receiving ACE inhibitors have been reported to have a higher incidence of angioedema compared to non-blacks. (See WARNINGS, Angioedema.)
Is using Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?
Enalapril maleate and Felodipine are the two main ingredients of Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg. Based on our individual analysis of Enalapril maleate and Felodipine we can safely say that Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg has low risk while breastfeeding. Below we have summarized the usage of Enalapril maleate and Felodipine while breastfeeding, we recommend you to go through it for better understanding of your usage.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Enalapril and enalaprilat are detected in human breast milk. It is not known whether felodipine administered as monotherapy is secreted in human milk; studies of the combination of enalapril and felodipine in rats indicate that felodipine concentrates in milk to a level almost ten-fold that found in plasma. Because of the potential for serious adverse reactions from enalapril and felodipine in the infant, a decision should be made either to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Therefore, caution should be exercised when LEXXEL is given to a nursing mother.
Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg Breastfeeding Analsys
Enalapril maleate while Breastfeeding Safe
CAS Number: 75847-73-3
Excretion into breast milk is clinically non-significant. No harmful effects among breastfed infants from treated mothers have been found. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Felodipine while Breastfeeding Low Risk
CAS Number: 72509-76-3
At latest update no published data were found on excretion into breast milk. Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount.Its high plasma protein binding capacity makes it highly unlikely a passage into milk. It has been described an increased Prolactin plasma level and gynecomastia after using Felodipine. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants.
Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg Breastfeeding Analsys - 2
Enalapril maleate while Breastfeeding
CAS Number: 75847-73-3
Because of the low levels of enalapril in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
Felodipine while Breastfeeding
CAS Number: 72509-76-3
Because no information is available on the use of felodipine during breastfeeding, an alternate drug may be preferred.
I already used Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg and meanwhile I breastfed my baby should I be concerned?
Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg so you should inform him based on your convenience.
My health care provider has asked me to use Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg, what to do?
Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.
If I am using Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg, will my baby need extra monitoring?
Not much monitoring required while using Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg
Who can I talk to if I have questions about usage of Lexxel | Enalapril Maleate 1 Mg, Felodipine 1 Mg in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week