Most health expert recommend six month of exclusive breastfeeding but statics suggest that numbers are not good, almost 95% mothers start breastfeeding but this number drops to 40% in first three month and further it drops to 15% till fifth month. Sometime its due to need of medication usage. Because of these statics its important to provide good information on safety of drugs in breastfeeding so that it can be improved when possible. In this FAQ sheet we will discuss about exposure to Captopril And Hydrochlorothiazide Tablet while breastfeeding. We will also discuss about common side effects and warnings associated with Captopril And Hydrochlorothiazide Tablet.
What is Captopril And Hydrochlorothiazide Tablet used for?
Captopril and Hydrochlorothiazide tablets are indicated for the treatment of hypertension. The blood pressure lowering effects of captopril and thiazides are approximately additive. This fixed combination drug may be used as initial therapy or substituted for previously titrated doses of the individual components. When captopril and hydrochlorothiazide are given together it may not be necessary to administer captopril in divided doses to attain blood pressure control at trough (before the next dose). Also, with such a combination, a daily dose of 15 mg of hydrochlorothiazide may be adequate. Treatment may, therefore, be initiated with Captopril and Hydrochlorothiazide tablets 25 mg/15 mg once daily. Subsequent titration should be with additional doses of the components (captopril, hydrochlorothiazide) as single agents or as Captopril and Hydrochlorothiazide tablets 50 mg/15 mg, 25 mg/25 mg, or 50 mg/25 mg (see DOSAGE AND ADMINISTRATION). In using Captopril and Hydrochlorothiazide tablets, consideration should be given to the risk of neutropenia/agranulocytosis (seeWARNINGS). Captopril and Hydrochlorothiazide tablets may be used for patients with normal renal function, in whom the risk is relatively low. In patients with impaired renal function, particularly those with collagen vascular disease, Captopril and Hydrochlorothiazide tablets should be reserved for hypertensives who have either developed unacceptable side effects on other drugs, or have failed to respond satisfactorily to other drug combinations. ACE inhibitors (for which adequate data are available) cause a higher rate of angioedema in black than in non-black patients (seeWARNINGS: Angioedema).
What are the risk associated with Captopril And Hydrochlorothiazide Tablet usage while breastfeeding? What precautions shall I take while using it in breastfeeding?
Captopril And Hydrochlorothiazide Tablet is primarily made of two things Captopril, Hydrochlorothiazide. What we have done here is we have analyzed Captopril for its impact on breastfeeding and analyzed Hydrochlorothiazide for its impact on breastfeeding. Our analysis of Captopril and Hydrochlorothiazide suggests that Captopril And Hydrochlorothiazide Tablet is probably safe in breastfeeding however we suggest you to check detail about both below.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Both captopril and hydrochlorothiazide are excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from both drugs, a decision should be made whether to discontinue nursing or to discontinue therapy taking into account the importance of Captopril and Hydrochlorothiazide to the mother. (See PRECAUTIONS: Pediatric Use.)
Captopril And Hydrochlorothiazide Tablet Breastfeeding Analsys
Captopril while Breastfeeding Safe
CAS Number: 62571-86-2
Excreted into breast milk in non-significant amount without harm effects observed among breastfed infants of mothers treated with Captopril. The American Academy of Pediatrics rates it as usually compatible with Breastfeeding.
Hydrochlorothiazide while Breastfeeding Safe
CAS Number: 58-93-5
Thiazide diuretic drug. Excretion into breast milk is clinically non-significant. No side-effects were observed in a one-month old breastfed baby whose mother was treated with this medication. Drug level in the plasma of this child was undetectable. Long-term treatment with diuretic drugs (particularly Thiazide type ones with long-lasting effect and loop-acting mechanism) may inhibit lactation, mostly if lactation is not well-established yet. Use as lower dose as possible, especially during the first postnatal month. American Academy of Pediatrics 2013: Maternal Medication Usually Compatible With Breastfeeding. WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.
Captopril And Hydrochlorothiazide Tablet Breastfeeding Analsys - 2
Captopril while Breastfeeding
CAS Number: 62571-86-2
Because of the low levels of captopril in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
Hydrochlorothiazide while Breastfeeding
CAS Number: 58-93-5
Hydrochlorothiazide doses of 50 mg daily or less are acceptable during lactation. Intense diuresis with large doses may decrease breastmilk production.
What should I do if already breastfed my kid after using Captopril And Hydrochlorothiazide Tablet?
It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Captopril And Hydrochlorothiazide Tablet and have used it then do not panic as Captopril And Hydrochlorothiazide Tablet is mostly safe in breastfeeding and should not cause any harm to your baby.
I am nursing mother and my doctor has suggested me to use Captopril And Hydrochlorothiazide Tablet, is it safe?
Usage of Captopril And Hydrochlorothiazide Tablet is safe for nursing mothers and baby, No worries.
If I am using Captopril And Hydrochlorothiazide Tablet, will my baby need extra monitoring?
Who can I talk to if I have questions about usage of Captopril And Hydrochlorothiazide Tablet in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week