CAS Number: 1405-20-5
Antibiotic drug that is usual topically used (Dermatology, ENT and Ophthalmology) At latest update no published data on excretion into breast milk were found. The small dose and low absorption to the plasma in a majority of preparations that are topically used on the eye, ear or skin make a significant excretion into the milk unlikely. Its high molecular weight makes less probable an excretion into breast milk in significant amount. Due to a poor oral bioavailability, appearance in the infant's plasma from ingested milk is regarded as nil or scanty, except in premature infants or during the immediate neonatal period who may show an increased intestinal absorption. Polymyxin E or Colistin with a very similar molecular structure is excreted into breast milk in non-significant amount. It is advisable to avoid the application of creams, gels and other products for local use that would contain paraffin (mineral oil) to prevent absorption by the infant.
CAS Number: 738-70-5
It is excreted in breast milk in clinically non-significant amount. No problems have been observed in infants whose mothers were treated. Medication which is used in infants from the second month of age. Take into account the possibility of negative false results of cultures from febrile infants whose mothers are taking antibiotics as well as the possibility of acute diarrhea due to imbalance of the intestinal flora. The American Academy of Pediatric states that it is usually compatible with breastfeeding medication.WHO List of Essential Medicines from 2002 has classified it as compatible with breastfeeding.
CAS Number: 1404-26-8
Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.
CAS Number: 738-70-5
Because of the low levels of trimethoprim in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
As usage of Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops else no further action is required.
Definitely, Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops is safe in lactation for baby. No wonder your doctor has recommended it.
No extra baby monitoring required while mother is using Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops
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