Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops while Breastfeeding

Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops is safe in breast-feeding or not.

What is Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops used for?


Polymyxin B sulfate and trimethoprim ophthalmic solution is indicated in the treatment of surface ocular bacterial infections, including acute bacterial conjunctivitis, and blepharoconjunctivitis, caused by susceptible strains of the following microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus viridans, Haemophilus influenzae and Pseudomonas aeruginosa.** **Efficacy for this organism in this organ system was studied in fewer than 10 infections.

Can I continue breastfeeding if I am using Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops? How long does it stays in breast milk?

Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops safe for breastfeeding
Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops is primarily made of two things Polymyxin b, Trimethoprim. What we have done here is we have analyzed Polymyxin b for its impact on breastfeeding and analyzed Trimethoprim for its impact on breastfeeding. Our analysis of Polymyxin b and Trimethoprim suggests that Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops is probably safe in breastfeeding however we suggest you to check detail about both below.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when polymyxin B sulfate and trimethoprim ophthalmic solution is administered to a nursing woman.

Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops Breastfeeding Analsys


Polymyxin b while Breastfeeding

Safe

CAS Number: 1405-20-5

Antibiotic drug that is usual topically used (Dermatology, ENT and Ophthalmology) At latest update no published data on excretion into breast milk were found. The small dose and low absorption to the plasma in a majority of preparations that are topically used on the eye, ear or skin make a significant excretion into the milk unlikely. Its high molecular weight makes less probable an excretion into breast milk in significant amount. Due to a poor oral bioavailability, appearance in the infant's plasma from ingested milk is regarded as nil or scanty, except in premature infants or during the immediate neonatal period who may show an increased intestinal absorption. Polymyxin E or Colistin with a very similar molecular structure is excreted into breast milk in non-significant amount. It is advisable to avoid the application of creams, gels and other products for local use that would contain paraffin (mineral oil) to prevent absorption by the infant.

Trimethoprim while Breastfeeding

Safe

CAS Number: 738-70-5

It is excreted in breast milk in clinically non-significant amount. No problems have been observed in infants whose mothers were treated. Medication which is used in infants from the second month of age. Take into account the possibility of negative false results of cultures from febrile infants whose mothers are taking antibiotics as well as the possibility of acute diarrhea due to imbalance of the intestinal flora. The American Academy of Pediatric states that it is usually compatible with breastfeeding medication.WHO List of Essential Medicines from 2002 has classified it as compatible with breastfeeding.


Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops Breastfeeding Analsys - 2


Polymyxin b while Breastfeeding

CAS Number: 1404-26-8

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Trimethoprim while Breastfeeding

CAS Number: 738-70-5

Because of the low levels of trimethoprim in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.



I am nursing mother and I have already used Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops, what should I do?

As usage of Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops else no further action is required.


My health care provider has asked me to use Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops, what to do?

Definitely, Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops is safe in lactation for baby. No wonder your doctor has recommended it.


If I am using Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops, will my baby need extra monitoring?

No extra baby monitoring required while mother is using Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops


Who can I talk to if I have questions about usage of Polymyxin B Sulfate And Trimethoprim Sulfate Solution/ Drops in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week