It is recommended to breastfeed exclusively for six months and then while introducing to other food sources extend it to twelve months. In this duration most mothers will need help of some sort of medication, It could be for short term like could and flue or it could be something chronic like Arthritis or Diabetes and here comes the question of safety of medication in use. In this post we will figure out what is Ddavp | Desmopressin Acetate Solution and whether its safe to use Ddavp | Desmopressin Acetate Solution while nursing or not.
What is Ddavp | Desmopressin Acetate Solution used for?
Hemophilia A DDAVP Injection 4 mcg/mL is indicated for patients with hemophilia A with factor VIII coagulant activity levels greater than 5%. DDAVP will often maintain hemostasis in patients with hemophilia A during surgical procedures and postoperatively when administered 30 minutes prior to scheduled procedure. DDAVP will also stop bleeding in hemophilia A patients with episodes of spontaneous or trauma-induced injuries such as hemarthroses, intramuscular hematomas or mucosal bleeding. DDAVP is not indicated for the treatment of hemophilia A with factor VIII coagulant activity levels equal to or less than 5%, or for the treatment of hemophilia B, or in patients who have factor VIII antibodies. In certain clinical situations, it may be justified to try DDAVP in patients with factor VIII levels between 2% to 5%; however, these patients should be carefully monitored. von Willebrand's Disease (Type I) DDAVP Injection 4 mcg/mL is indicated for patients with mild to moderate classic von Willebrand's Disease (Type I) with factor VIII levels greater than 5%. DDAVP will often maintain hemostasis in patients with mild to moderate von Willebrand's Disease during surgical procedures and postoperatively when administered 30 minutes prior to the scheduled procedure. DDAVP will usually stop bleeding in mild to moderate von Willebrand's patients with episodes of spontaneous or trauma-induced injuries such as hemarthroses, intramuscular hematomas or mucosal bleeding. Those von Willebrand's disease patients who are least likely to respond are those with severe homozygous von Willebrand's disease with factor VIII coagulant activity and factor VIII von Willebrand factor antigen levels less than 1%. Other patients may respond in a variable fashion depending on the type of molecular defect they have. Bleeding time and factor VIII coagulant activity, ristocetin cofactor activity, and von Willebrand factor antigen should be checked during administration of DDAVP to ensure that adequate levels are being achieved. DDAVP is not indicated for the treatment of severe classic von Willebrand's Disease (Type I) and when there is evidence of an abnormal molecular form of factor VIII antigen. (See WARNINGS.) Diabetes Insipidus DDAVP Injection 4 mcg/mL is indicated as antidiuretic replacement therapy in the management of central (cranial) diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. DDAVP is ineffective for the treatment of nephrogenic diabetes insipidus. DDAVP is also available as an intranasal preparation. However, this means of delivery can be compromised by a variety of factors that can make nasal insufflation ineffective or inappropriate. These include poor intranasal absorption, nasal congestion and blockage, nasal discharge, atrophy of nasal mucosa, and severe atrophic rhinitis. Intranasal delivery may be inappropriate where there is an impaired level of consciousness. In addition, cranial surgical procedures, such as transsphenoidal hypophysectomy, create situations where an alternative route of administration is needed as in cases of nasal packing or recovery from surgery.
What are the risk associated with Ddavp | Desmopressin Acetate Solution usage while breastfeeding? What precautions shall I take while using it in breastfeeding?
Active ingredient in Ddavp | Desmopressin Acetate Solution is Desmopressin acetate and based on our analysis of Desmopressin acetate it appears that using Ddavp | Desmopressin Acetate Solution is safe in breastfeeding. Below is analysis of Desmopressin acetate while breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers There have been no controlled studies in nursing mothers. A single study in postpartum women demonstrated a marked change in plasma, but little if any change in assayable DDAVP in breast milk following an intranasal dose of 10 mcg. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when DDAVP is administered to a nursing woman.
Ddavp | Desmopressin Acetate Solution Breastfeeding Analsys
Desmopressin acetate while Breastfeeding Safe
CAS Number: 16679-58-6
It is structurally analogue to the naturally occurring anti-diuretic vasopressin hormone.
Ddavp | Desmopressin Acetate Solution Breastfeeding Analsys - 2
Desmopressin acetate while Breastfeeding
CAS Number: 16679-58-6
Desmopressin from a nasal spray is excreted in negligible amounts into milk and is poorly absorbed orally by the infant, so it appears acceptable to use during breastfeeding. There is no published experience with sublingual desmopressin during breastfeeding. Until more data become available, sublingual desmopressin should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
What if I already have used Ddavp | Desmopressin Acetate Solution?
As usage of Ddavp | Desmopressin Acetate Solution is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Ddavp | Desmopressin Acetate Solution else no further action is required.
I am nursing mother and my doctor has suggested me to use Ddavp | Desmopressin Acetate Solution, is it safe?
Usage of Ddavp | Desmopressin Acetate Solution is safe for nursing mothers and baby, No worries.
If I am using Ddavp | Desmopressin Acetate Solution, will my baby need extra monitoring?
Who can I talk to if I have questions about usage of Ddavp | Desmopressin Acetate Solution in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week