Nephrocaps while Breastfeeding

What is Nephrocaps used for?

Is Nephrocaps usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Ascorbic acid while Breastfeeding

CAS Number: 50-81-7

Vitamin C is abundantly present in food. A balanced and comprehensive diet makes vitamin supplementation useless. Any amount of vitamin C taken by the mother as a supplement does not affect significantly the concentration in breast milk of women who are on a varied and balanced diet.

Thiamine while Breastfeeding

CAS Number: 59-43-8

Thiamine or Vitamin B1 is a water soluble vitamin. In addition to Thiamine, other chemical compounds with similar activity: Acetiamine, Benfotiamine, Bisbentiamine, Bisbutiamina, Cetotiamina, Cicotiamina, Cocarboxylase, Fursultiamine, Monofosfotiamina, Octotiamine, Pyrophosphotiamine, Prosultiamine and Sulbutiamine.It is essential for the metabolism of carbohydrate nutrients. Its deficiency causes severe neuromuscular and cardiac symptoms known as Beriberi and Wernicke-Korsakoff disease. Thiamine deficiency is common among disadvantaged populations in Southeast Asia (predominantly consumers of refined rice), other malnourished people (refugees, low socioeconomic status ...) and chronic alcohol consumption. Beriberi of childhood, both infants and children, may arise from breastfeeding by Thiamine deficient mothers. Reportedly, several severe cases have occured after feeding the babies with artificial formulas that were not supplemented with vitamin B1. Daily allowance is higher during pregnancy and lactation (1.5 mg / day) which is readily obtained through a varied diet with adequate content of whole grains, legumes, nuts, eggs and lean meat.Thiamine is excreted in breast milk and gradually increases with time, being lower in colostrum (28 ng / mL) and transitional milk than in mature milk (180 ng / mL). The concentration is lower in milk from mothers of preterm (90 ng / mL). Taking vitamin supplementation is not required if diet and nutritional status are adequate. Supplementation does not increase levels in milk of well-nourished women, but of those with a low nutritional status. The supplementation of group B vitamins and C and E vitamins to HIV positive mothers improves the weight growth of their breasted babies.There is no evidence of their effectiveness in improving athletic performance, lack of appetite, sores, stress, fatigue or aging.Toxicity linked to excessive consumption of thiamine is not known. WHO List of Essential Medicines 2002: compatible with breastfeeding.American Academy of Pediatrics: usually compatible with breastfeeding

Riboflavin while Breastfeeding

CAS Number: 83-88-5

A balanced and comprehensive diet make it vitamin supplementation useless.

Pyridoxine while Breastfeeding

CAS Number: 65-23-6

Concentration of vitamin B6 in the breast milk is directly related to the amount present in diet with the possibility of a high increment by an excessive consumption through the diet. Daily allowance of vitamin B6 ranges from 2 to 3 mg. A balanced and varied diet is enough without a need for extra supplementation with this vitamin. Vitamin B6 deficiency is extremely rare since it is widely distributed in many foods. In those cases where supplementation is required, it is recommended not to exceed 40 mg a-day. There are controversial data on the capacity of a high dose of Pyridoxine to inhibit the secretion of Prolactin and suppress the milk production. The American Academy of Pediatrics rates it as usually compatible with breastfeeding.

Folic acid while Breastfeeding

CAS Number: 59-30-3

Soluble B group vitamin that is very abundant in green vegetables, legumes and fruits (citric fruits). It is actively excreted in breast milk with priority over maternal folate in such extent that may even cause maternal deficit. Exclusive breastfeeding meets the daily allowances of infant folic acid.The concentration is higher in mature milk (85 micrograms / L) than in colostrum and premature breast milk.Administration to nursing mothers increases slightly the usual concentration of folate in breast milk. Folic acid needs are increased during pregnancy and lactation (500-600 micrograms / day) and in case of taking anticonvulsant medication. No harmful effects have been observed by taking folic acid during lactation. Excess of folic acid is eliminated by the kidneys every day. No supplements are needed if diet and nutritional status are adequate. The American Academy of Pediatrics rates it as a mediation usually compatible with breastfeeding.WHO List of Essential Medicines 2002: compatible with breastfeeding.

Cyanocobalamin while Breastfeeding

CAS Number: 68-19-9

Vitamin B12 exists naturally in milk at a concentration of 1 nanogram / mL (range: 0.3 to 3 ng / mL). Maternal supplementation with cyanocobalamin barely increases milk levels in well-nourished women (Sandberg 1981), but it does improve the levels in women of low socioeconomic status (Sneed 1981). The concentration in colostrum is up to 28 times higher than that of mature milk.The daily requirements for Vitamin B12 are 2.4 micrograms and increase to 2.8 micrograms daily during breastfeeding. Foods rich in vitamin B12 are meat, offal, eggs, dairy products, salmon, sardines, clams and fortified cereals. With a varied and balanced diet no vitamin supplements are needed, but B12 deficiency has been observed in the plasma and milk of women with strict vegetarian diets (vegans), malabsorptive diseases (eg, Crohn's disease, celiac disease), bariatric surgery, poor nutritional status, pernicious anemia, low socio-economic status and in cases of natural disasters or wars. There are numerous publications showing that infants of these mothers are at high risk of disease due to vitamin B12 deficiency, which can lead to anemia, stunting and psychomotor retardation. "Flash pasteurization" applied to breast milk of mothers who are HIV+ does not decrease vitamin B12 concentration. American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).

Biotin while Breastfeeding

CAS Number: 58-85-5

It is an essential co-enzyme for fat metabolism and other metabolic reactions, which is classified among the vitamin B group. Recommended daily allowance is 10 to 200 μg according to some authorities and 30 to 100 μg to some others. (5 at15 μg for infants, 20 to 30 μg for children, 30 μg for pregnant women and 35 μg for lactating mothers). Biotin is found in the non-fat fraction of breast milk in an amount of 5 to 9 μg/L. Biotin is widely distributed in most foods with a very rare occurrence of deficiency among people who are on adequate diet, nor any case of intoxication is known even with higher doses than recommended for daily intake. At date of latest update, relevant data related to breastfeeding were not found. However, because lack of toxicity a risk due to consumption at recommended dose is unlikely. With an adequate and comprehensive diet, the consumption of vitamin supplementation is not necessary.

Pantothenic acid while Breastfeeding

CAS Number: 79-83-4

Pantothenic acid, dexpanthenol or vitamin B5 is widely distributed in nature being very abundant in meat, vegetables, cereals, legumes, eggs, milk, fruit and vegetables (MedlinePlus 2015), therefore its deficiency is very rare. The only recognized indication for administering pantothenic acid is to treat vitamin B5 deficiency. There is no evidence that it can be used to treat any other disease or condition. (MedlinePlus 2015). Daily requirements are 2 mg in infants, 4 in children, 5 in adults, 6 in pregnant women and 7 mg in breastfeeding mothers (Ares 2015, MedlinePLus 2015). Pantothenic acid is excreted in breast milk at a concentration of 2 to 2.7 mg/L (Sakurai 2005, Song 1984) with little variation throughout breastfeeding (Ren 2015, Johnston 1981) and is directly proportional to maternal ingestion (Song 1984, Johnston 1981). The concentration is higher in milk of mothers of premature babies than in full-term infants (Ford 1983). With a varied and balanced diet, supplements of this vitamin are not needed during breastfeeding, it is enough to adequately select the food in one’s diet (Song 1985). Topical use, most commonly used as panthenol or provitamin B5, regardless of its questionable efficacy, is compatible with breastfeeding.

Cyanocobalamin while Breastfeeding

CAS Number: 68-19-9

Vitamin B12 is a normal component of human milk.[1] The recommended daily intake in lactating women is 2.8 mcg and for infants aged 6 months or less is 0.4 mcg.[2] Lactating mothers may need to supplement their diet to achieve the recommended daily intake or to correct a known deficiency. Low doses of vitamin B12 found in B complex or prenatal vitamins increase milk levels only slightly. Higher daily doses of 50 to 100 mcg or more are needed in cases of maternal deficiency. The breastfed infant is not exposed to excessive vitamin B12 in such cases, and their vitamin B12 status should improve if it was previously inadequate. Poor health outcomes in infants with vitamin B12 deficiency include anemia, abnormal skin and hair development, convulsions, failure to thrive, and mental developmental delay. One well-recognized at risk group are exclusively breastfed infants of mothers with B12 deficiency due to minimal or no dietary intake of animal products.[3][4][5][6][7][8][9] Infant vitamin B12 status can be improved through maternal B12 supplementation during pregnancy and lactation.[10][11][12][13] Deficient mothers who miss the opportunity to supplement during pregnancy should still be encouraged to supplement during early lactation since infant vitamin B12 status correlates with milk vitamin B12 levels in breastfed infants up to 6 months of age.[14][15][16][17] Although there are cases reported of exclusively breastfed infants with vitamin B12 deficiency having biochemical and clinical improvement through adequate maternal supplementation alone,[3] direct supplementation of the infant is recommended when such treatments are available.[18][19][8] Flash heat pasteurization of breastmilk does not reduce milk vitamin B12 concentration.[20]

I already used Nephrocaps and meanwhile I breastfed my baby should I be concerned?

I am nursing mother and my doctor has suggested me to use Nephrocaps, is it safe?

If I am using Nephrocaps, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Nephrocaps in breastfeeding?