Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment Breastfeeding

There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment and its suitability with breastfeeding.

What is Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment ?


CORTISPORIN Ophthalmic Ointment is indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial infection exists. Ocular corticosteroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of corticosteroid use in certain infective conjunctivitides is accepted to obtain a diminution in edema and inflammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies. The use of a combination drug with an anti-infective component is indicated where the risk of infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye (see CLINICAL PHARMACOLOGY: Microbiology). The particular anti-infective drugs in this product are active against the following common bacterial eye pathogens: Staphylococcus aureus , streptococci, including Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzae, Klebsiella/Enterobacter species, Neisseria species, and Pseudomonas aeruginosa. The product does not provide adequate coverage against Serratia marcescens.

Can I use Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment while breastfeeding?

Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment is made up of Neomycin, Polymyxin b, Bacitracin zinc, Hydrocortisone.Below is the analysis of usage of its active ingredients while breastfeeding, We suggest you to go through full analysis to understand the impact of Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment in breastfeeding.Please note that we have already provided safety rating to some of the ingredients but other ingredients does not have any safety rating and we are working on it.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. Because of the potential for serious adverse reactions in nursing infants from CORTISPORIN Ophthalmic Ointment, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment Breastfeeding Analsys


Neomycin while Breastfeeding

Safe

CAS Number: 1404-04-2

Aminoglycoside antibiotic which is used in creams, eye drops, and otologic preparations for topical use, and, also orally used for intestinal disinfection. At latest update, relevant published data on excretion in the breast milk were not found. Like other aminoglycoside antibiotics, Neomycin is not absorbed by the gut. Absorption from other sources like skin, nose, ear and eye mucosa by means of topically used preparations (creams, drops, etc.) is very poor which causes excretion into breast milk in significant amount, unlikely. Do not apply creams, gels and other products that would contain paraffin (mineral oil) to avoid absorption by the infant since it is a hydrocarbon-derived substance. In case of use of Neomycin on the nipple, let it be done after the feed and wipe it out any excess of cream before the next feed. Be aware of false negative results of microbial cultures done from samples of febrile infants whose mothers are treated with antibiotics. Also, due to imbalance of intestinal flora a diarrheal disease can occur in the breastfed infant. List of Essential Medicines by WHO 2002: compatible with breastfeeding.

Polymyxin b while Breastfeeding

Safe

CAS Number: 1405-20-5

Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment and breastfeeding

Antibiotic drug that is usual topically used (Dermatology, ENT and Ophthalmology) At latest update no published data on excretion into breast milk were found. The small dose and low absorption to the plasma in a majority of preparations that are topically used on the eye, ear or skin make a significant excretion into the milk unlikely. Its high molecular weight makes less probable an excretion into breast milk in significant amount. Due to a poor oral bioavailability, appearance in the infant's plasma from ingested milk is regarded as nil or scanty, except in premature infants or during the immediate neonatal period who may show an increased intestinal absorption. Polymyxin E or Colistin with a very similar molecular structure is excreted into breast milk in non-significant amount. It is advisable to avoid the application of creams, gels and other products for local use that would contain paraffin (mineral oil) to prevent absorption by the infant.

Hydrocortisone while Breastfeeding

Safe

CAS Number: 50-23-7

Cortisol is a normal component of breast milk. Although unlikely to achieve harmful levels for the infant, it is preferred the use of an alternative (Methylprednisolone, Prednisolone, Prednisone). Intra-articular administration of depot prednisone derivatives may be a cause of transient decrease of milk production. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.


Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment Breastfeeding Analsys - 2


Neomycin while Breastfeeding

CAS Number: 1404-04-2

Although no information exists on the excretion of neomycin into milk, other aminoglycoside antibiotics are poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of aminoglycosides, but serum levels are far below those attained when treating newborn infections and systemic effects of neomycin are unlikely. Older infants would be expected to absorb even less neomycin. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. Oral, topical, ophthalmic or otic neomycin should result in very low levels in breastmilk and present negligible risk to the infant,[1][2] although topical application to the nipple may increase the risk of diarrhea in the infant. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]

Polymyxin b while Breastfeeding

CAS Number: 1404-26-8

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Bacitracin zinc while Breastfeeding

CAS Number: 1405-87-4

Because it is poorly absorbed after topical application and oral ingestion, bacitracin is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Hydrocortisone while Breastfeeding

CAS Number: 50-23-7

Is Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment safe while breastfeeding

Hydrocortisone (cortisol) is a normal component of breastmilk that passes from the mother's bloodstream into milk and might have a role in intestinal maturation, the intestinal microbiome, growth, body composition or neurodevelopment, but adequate studies are lacking.[1] Concentrations follow a diurnal rhythm, with the highest concentrations in the morning at about 7:00 am and the lowest concentrations in the late afternoon and evening.[2][3] Cortisol in milk may protect against later infant obesity, especially in girls.[4] Hydrocortisone has not been studied in breastmilk after exogenous administration in pharmacologic amounts. Hydrocortisone in breastmilk is stable at room temperature and during repeated freeze-thaw cycles.[5] Although it is unlikely that dangerous amounts of hydrocortisone would reach the infant, a better studied alternate corticosteroid might be preferred. Maternal use of hydrocortisone as an enema would not be expected to cause any adverse effects in breastfed infants. Local maternal injections, such as for tendinitis, would not be expected to cause any adverse effects in breastfed infants, but might occasionally cause temporary loss of milk supply. See also Hydrocortisone, Topical. Hydrocortisone concentrations in breastmilk are not affected by storage for 36 hours at room temperature, during multiple freeze-thaw cycles, nor Holder pasteurization (62.5 degrees C for 30 minutes).[5][6]


Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment safe for breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment?

We are not completely sure about safety of Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment in breastfeeding. We would suggest you to contact your doctor or health care provider and explain your situation with Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment. If you observe anything abnormal with your baby please call 911 or contact emergency services in your area.


My doctor has prescribed me Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment, what should I do?

If your doctor considers Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment safe enough to prescribe for you that means its benefits outweigh its known risks.


If I am using Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment, will my baby need extra monitoring?

Not Sure, Please check with your doctor or lactation consultant.


Who can I talk to if I have questions about usage of Cortisporin | Neomycin And Polymyxin B Sulfates, Bacitracin Zinc,and Hydrocortisone Ointment in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week