Lotronex | Alosetron Hydrochloride Tablet Breastfeeding

There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Lotronex | Alosetron Hydrochloride Tablet and its suitability with breastfeeding.

What is Lotronex | Alosetron Hydrochloride Tablet used for?


LOTRONEX is indicated only for women with severe diarrhea-predominant irritable bowel syndrome (IBS) who have: chronic IBS symptoms (generally lasting 6 months or longer), had anatomic or biochemical abnormalities of the gastrointestinal tract excluded, and not responded adequately to conventional therapy. Diarrhea-predominant IBS is severe if it includes diarrhea and one or more of the following: frequent and severe abdominal pain/discomfort frequent bowel urgency or fecal incontinence disability or restriction of daily activities due to IBS Because of infrequent but serious gastrointestinal adverse events associated with LOTRONEX, the indication is restricted to those patients for whom the benefit-to-risk balance is most favorable. Clinical studies have not been performed to adequately confirm the benefits of LOTRONEX in men.

What are the risk associated with Lotronex | Alosetron Hydrochloride Tablet usage while breastfeeding? What precautions shall I take while using it in breastfeeding?

Lotronex | Alosetron Hydrochloride Tablet low risk for breastfeeding
Alosetron hydrochloride is the one and only active ingredient present in Lotronex | Alosetron Hydrochloride Tablet. Alosetron hydrochloride in itself is a low risk drug for lactation so it is easy to understand that Lotronex | Alosetron Hydrochloride Tablet also comes in category of Low Risk item while breastfeeding. Below is the summary of Alosetron hydrochloride in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Alosetron and/or metabolites of alosetron are excreted in the breast milk of lactating rats. It is not known whether alosetron is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when LOTRONEX is administered to a nursing woman.

Lotronex | Alosetron Hydrochloride Tablet Breastfeeding Analsys


Alosetron hydrochloride while Breastfeeding

Low Risk

CAS Number: 122852-42-0

Cases of severe intestinal side effects have been reported. On latest update no published data about breastfeeding were found. Because a rapid metabolic rate and poor oral absorption - when taken along with food - this drug is probably safe while breastfeeding. Safety would increase if a 3-hour period is observed before resuming breastfeeding.


Lotronex | Alosetron Hydrochloride Tablet Breastfeeding Analsys - 2


Alosetron hydrochloride while Breastfeeding

CAS Number: 122852-42-0

No information is available on the use of alosetron during breastfeeding. Because of relatively high protein binding and only moderate bioavailability, exposure of the breastfed infant is likely to be low. If alosetron is required by the mother, it is not a reason to discontinue breastfeeding. However, until more data are available alosetron should only be used with careful infant monitoring during breastfeeding.


Is Lotronex | Alosetron Hydrochloride Tablet safe while breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Lotronex | Alosetron Hydrochloride Tablet?

Lotronex | Alosetron Hydrochloride Tablet is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Lotronex | Alosetron Hydrochloride Tablet so you should inform him based on your convenience.


My health care provider has asked me to use Lotronex | Alosetron Hydrochloride Tablet, what to do?

Lotronex | Alosetron Hydrochloride Tablet comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Lotronex | Alosetron Hydrochloride Tablet, will my baby need extra monitoring?

Not much monitoring required while using Lotronex | Alosetron Hydrochloride Tablet


Who can I talk to if I have questions about usage of Lotronex | Alosetron Hydrochloride Tablet in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week