Alosetron Hydrochloride Tablet while Breastfeeding

For most of the drugs advantages of taking medications overweighs the potential risks however some drugs could be really dangerous for breastfed baby hence every medication shall be considered separately. In this page we will discuss about purpose of Alosetron Hydrochloride Tablet and its risk associated with lactation. We will also discuss the usage of Alosetron Hydrochloride Tablet and some common side effects associated with Alosetron Hydrochloride Tablet.

What is Alosetron Hydrochloride Tablet used for?


1. INDICATIONS AND USAGE Alosetron hydrochloride tablets are indicated only for women with severe diarrhea-predominant irritable bowel syndrome (IBS) who have: chronic IBS symptoms (generally lasting 6 months or longer), had anatomic or biochemical abnormalities of the gastrointestinal tract excluded, and not responded adequately to conventional therapy. Diarrhea-predominant IBS is severe if it includes diarrhea and one or more of the following: frequent and severe abdominal pain/discomfort, frequent bowel urgency or fecal incontinence, disability or restriction of daily activities due to IBS. Because of infrequent but serious gastrointestinal adverse reactions associated with alosetron hydrochloride tablets, the indication is restricted to those patients for whom the benefit-to-risk balance is most favorable. Clinical studies have not been performed to adequately confirm the benefits of alosetron hydrochloride tablets in men. Alosetron is a selective serotonin 5-HT3 antagonist indicated only for women with severe diarrhea-predominant irritable bowel syndrome (IBS) who have: chronic IBS symptoms (generally lasting 6 months or longer), had anatomic or biochemical abnormalities of the gastrointestinal tract excluded, and not responded adequately to conventional therapy. (1) Severe IBS includes diarrhea and 1 or more of the following: frequent and severe abdominal pain/discomfort, frequent bowel urgency or fecal incontinence, disability or restriction of daily activities due to IBS. (1)

I am breastfeeding mother and I am using Alosetron Hydrochloride Tablet. Can it have any bad effect on my kid? Shall I search for better alternative?

Alosetron Hydrochloride Tablet low risk for breastfeeding
Alosetron Hydrochloride Tablet contains only one active ingredient that is Alosetron. We have analyzed the usage of Alosetron in breastfeeding and our analysis suggest that Alosetron poses Low risk for infant while breastfeeding and hence Alosetron Hydrochloride Tablet itself shall be considered Low risk item for breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Alosetron and/or metabolites of alosetron are excreted in the breast milk of lactating rats. It is not known whether alosetron is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when alosetron hydrochloride tablets is administered to a nursing woman.

Alosetron Hydrochloride Tablet Breastfeeding Analsys


Alosetron while Breastfeeding

Low Risk

CAS Number: 122852-42-0

Cases of severe intestinal side effects have been reported. On latest update no published data about breastfeeding were found. Because a rapid metabolic rate and poor oral absorption - when taken along with food - this drug is probably safe while breastfeeding. Safety would increase if a 3-hour period is observed before resuming breastfeeding.


Alosetron Hydrochloride Tablet Breastfeeding Analsys - 2


Alosetron while Breastfeeding

CAS Number: 122852-42-0

No information is available on the use of alosetron during breastfeeding. Because of relatively high protein binding and only moderate bioavailability, exposure of the breastfed infant is likely to be low. If alosetron is required by the mother, it is not a reason to discontinue breastfeeding. However, until more data are available alosetron should only be used with careful infant monitoring during breastfeeding.


Alosetron Hydrochloride Tablet and breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Alosetron Hydrochloride Tablet?

Alosetron Hydrochloride Tablet is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Alosetron Hydrochloride Tablet so you should inform him based on your convenience.


I am nursing mother and my doctor has suggested me to use Alosetron Hydrochloride Tablet, is it safe?

Though Alosetron Hydrochloride Tablet dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Alosetron Hydrochloride Tablet, will my baby need extra monitoring?

Not much monitoring required while using Alosetron Hydrochloride Tablet


Who can I talk to if I have questions about usage of Alosetron Hydrochloride Tablet in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week