Metrogel | Metronidazole 7.5 Mg In 1 G Breastfeeding
Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Metrogel | Metronidazole 7.5 Mg In 1 G.

What is Metrogel | Metronidazole 7.5 Mg In 1 G used for?


METROGEL-VAGINAL is indicated in the treatment of bacterial vaginosis (formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, Corynebacterium vaginitis, or anaerobic vaginosis). NOTE: For purposes of this indication, a clinical diagnosis of bacterial vaginosis is usually defined by the presence of a homogeneous vaginal discharge that (a) has a pH of greater than 4.5, (b) emits a “fishy” amine odor when mixed with a 10% KOH solution, and (c) contains clue cells on microscopic examination. Gram's stain results consistent with a diagnosis of bacterial vaginosis include (a) markedly reduced or absent Lactobacillus morphology, (b) predominance of Gardnerella morphotype, and (c) absent or few white blood cells. Other pathogens commonly associated with vulvovaginitis, e.g., Trichomonas vaginalis, Chlamydia trachomatis, N. gonorrhoeae, Candida albicans, and Herpes simplex virus should be ruled out.

What are the risk associated with Metrogel | Metronidazole 7.5 Mg In 1 G usage while breastfeeding? What precautions shall I take while using it in breastfeeding?

Metrogel | Metronidazole 7.5 Mg In 1 G safe for breastfeeding
Metronidazole is the only one ingredient used in manufacturing of Metrogel | Metronidazole 7.5 Mg In 1 G, Which makes it easier to analyze its effect in breastfeeding. As per our analysis of Metronidazole it is safe to use Metrogel | Metronidazole 7.5 Mg In 1 G while lactating. We suggest you to check further details below about Metronidazole usage in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Specific studies of metronidazole levels in human milk following intravaginally administered metronidazole have not been performed. However, metronidazole is secreted in human milk in concentrations similar to those found in plasma following oral administration of metronidazole. Because of the potential for tumorigenicity shown for metronidazole in mouse and rat studies, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Metrogel | Metronidazole 7.5 Mg In 1 G Breastfeeding Analsys


Metronidazole while Breastfeeding

Safe

CAS Number: 443-48-1

Excreted into breast milk in a non-significant clinical amount. Not problems on breastfed infants of treated mothers were found. Plasma levels were low or undetectable in those infants. For a mother's dose of 400 mg three times-a-day, the intake of a breastfed infant would be less than 10% of the usual daily pediatric dose, whenever the breast-feed is done within 2-3 hours of mother's intake. Widely used for treatment of Giardia lamblia infections, even in small infants, without adverse effects reported. Metronidazole may produce a red discoloration of corporal fluids and bitter flavor of the milk with no harm effect on the child.


Metrogel | Metronidazole 7.5 Mg In 1 G Breastfeeding Analsys - 2


Metronidazole while Breastfeeding

CAS Number: 443-48-1

Metrogel | Metronidazole 7.5 Mg In 1 G and breastfeeding

With maternal intravenous and oral therapy, breastfed infants receive metronidazole in doses that are less than those used to treat infections in infants, although the active metabolite adds to the total infant exposure. Plasma levels of the drug and metabolite are measurable, but less than maternal plasma levels. Case reports of candidal infections and diarrhea have been reported, and a comparative trial suggested that oral and rectal colonization with might be more common in infants exposed to metronidazole. Neither topical nor vaginal metronidazole have been studied during breastfeeding. After vaginal administration, plasma levels are less than 2% of those after a 500 mg oral dose. After topical administration, blood levels are about 1% of the peak plasma levels after a 250 mg oral dose. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1] Because of the well demonstrated genotoxicity and mutagenicity in bacteria, carcinogenicity in animals, and possible mutagenicity in humans,[2][3] concern has been raised about exposure of healthy infants to metronidazole via breastmilk.[4] The relevance of these findings has been questioned and no definitive study has yet been performed in humans.[3][5] Opinions vary among experts on the advisability of using metronidazole during longer-term therapy while breastfeeding, but some sources recommend discontinuing breastfeeding for 12 to 24 hours after single-dose maternal treatment.[4][6] Other drugs are available for some conditions that metronidazole is used to treat. Topical or vaginal use of metronidazole during breastfeeding is unlikely to be of concern, although the manufacturer of one vaginal product recommends not breastfeeding during treatment and for 2 days after the last dose.


Is Metrogel | Metronidazole 7.5 Mg In 1 G safe while breastfeeding

I already used Metrogel | Metronidazole 7.5 Mg In 1 G and meanwhile I breastfed my baby should I be concerned?

As usage of Metrogel | Metronidazole 7.5 Mg In 1 G is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Metrogel | Metronidazole 7.5 Mg In 1 G else no further action is required.


I am nursing mother and my doctor has suggested me to use Metrogel | Metronidazole 7.5 Mg In 1 G, is it safe?

Usage of Metrogel | Metronidazole 7.5 Mg In 1 G is safe for nursing mothers and baby, No worries.


If I am using Metrogel | Metronidazole 7.5 Mg In 1 G, will my baby need extra monitoring?

No


Who can I talk to if I have questions about usage of Metrogel | Metronidazole 7.5 Mg In 1 G in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week