Nutrients from the food that you eat passes to your breast milk. Its good idea to take healthy diet while breastfeeding. You may need to consume more calories per day to support healthy body system. Some time it gets necessary take medicine while you are breastfeeding and as other food items passes into breast milk, medicine passes as well hence it becomes obvious to understand its effects while breastfeeding. We have analyzed many medications and in this sheet we will present some fact and known information associated with Bosulif | Bosutinib Monohydrate Tablet while breast-feeding.
What is Bosulif | Bosutinib Monohydrate Tablet used for?
BOSULIF is indicated for the treatment of adult patients with chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) with resistance or intolerance to prior therapy. BOSULIF is a kinase inhibitor indicated for the treatment of adult patients with chronic, accelerated, or blast phase Ph+ chronic myelogenous leukemia (CML) with resistance or intolerance to prior therapy. (1)
What are the risk associated with Bosulif | Bosutinib Monohydrate Tablet usage while breastfeeding? What precautions shall I take while using it in breastfeeding?
Bosulif | Bosutinib Monohydrate Tablet contains Bosutinib monohydrate as active ingredients, . We do not have safety rating of Bosutinib monohydrate but we do have analysis of Bosutinib monohydrate, which is used in manufacturing of Bosulif | Bosutinib Monohydrate Tablet. You can get a good idea about Bosulif | Bosutinib Monohydrate Tablet usage while breastfeeding by going through our detailed analysis as below.
Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether bosutinib is excreted in human milk. Bosutinib and/or its metabolites were excreted in the milk of lactating rats. Radioactivity was present in the plasma of suckling offspring 24 to 48 hours after lactating rats received a single oral dose of radioactive bosutinib. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from BOSULIF, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Bosulif | Bosutinib Monohydrate Tablet Breastfeeding Analsys
Bosutinib monohydrate while Breastfeeding
CAS Number: 380843-75-4
No information is available on the clinical use of bosutinib during breastfeeding. Because bosutinib is 96% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 22 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during bosutinib therapy.
I am nursing mother and I have already used Bosulif | Bosutinib Monohydrate Tablet, what should I do?
We are not completely sure about safety of Bosulif | Bosutinib Monohydrate Tablet in breastfeeding. We would suggest you to contact your doctor or health care provider and explain your situation with Bosulif | Bosutinib Monohydrate Tablet. If you observe anything abnormal with your baby please call 911 or contact emergency services in your area.
I am nursing mother and my doctor has suggested me to use Bosulif | Bosutinib Monohydrate Tablet, is it safe?
If your doctor considers Bosulif | Bosutinib Monohydrate Tablet safe enough to prescribe for you that means its benefits outweigh its known risks.
If I am using Bosulif | Bosutinib Monohydrate Tablet, will my baby need extra monitoring?
Not Sure, Please check with your doctor or lactation consultant.
Who can I talk to if I have questions about usage of Bosulif | Bosutinib Monohydrate Tablet in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week