Renova | Tretinoin Cream while Breastfeeding

It is recommended to breastfeed exclusively for six months and then while introducing to other food sources extend it to twelve months. In this duration most mothers will need help of some sort of medication, It could be for short term like could and flue or it could be something chronic like Arthritis or Diabetes and here comes the question of safety of medication in use. In this post we will figure out what is Renova | Tretinoin Cream and whether its safe to use Renova | Tretinoin Cream while nursing or not.

What is Renova | Tretinoin Cream used for?


: (To understand fully the indication for this product, please read the entire INDICATIONS AND USAGE section of the labeling.) RENOVA (tretinoin emollient cream) 0.05% is indicated as an adjunctive agent (see second bullet point below) for use in the mitigation (palliation) of fine wrinkles, mottled hyperpigmentation, and tactile roughness of facial skin in patients who do not achieve such palliation using comprehensive skin care and sun avoidance programs alone (see bullet point 3 for populations in which effectiveness has not been established). RENOVA DOES NOT ELIMINATE WRINKLES, REPAIR SUN DAMAGED SKIN, REVERSE PHOTO-AGING, or RESTORE A MORE YOUTHFUL or YOUNGER DERMAL HISTOLOGIC PATTERN. Many patients achieve desired palliative effects on fine wrinkling, mottled hyperpigmentation, and tactile roughness of facial skin with the use of comprehensive skin care and sun avoidance programs including sunscreens, protective clothing, and emollient creams NOT containing tretinoin. RENOVA has demonstrated NO MITIGATING EFFECT on significant signs of chronic sun exposure such as coarse or deep wrinkling, skin yellowing, lentigines, telangiectasia, skin laxity, keratinocytic atypia, melanocytic atypia, or dermal elastosis. RENOVA should only be used under medical supervision as an adjunct to a comprehensive skin care and sun avoidance program that includes the use of effective sunscreens (minimum SPF of 15) and protective clothing when desired results on fine wrinkles, mottled hyperpigmentation, and roughness of facial skin have not been achieved with a comprehensive skin care and sun avoidance program alone. The effectiveness of RENOVA in the mitigation of fine wrinkles, mottled hyperpigmentation, and tactile roughness of facial skin has not been established in people greater than 50 years of age OR in people with moderately to heavily pigmented skin. In addition, patients with visible actinic keratoses and patients with a history of skin cancer were excluded from clinical trials of RENOVA. Thus the effectiveness and safety of RENOVA in these populations are not known at this time. Neither the safety nor the effectiveness of RENOVA for the prevention or treatment of actinic keratoses or skin neoplasms has been established. Neither the safety nor the efficacy of using RENOVA daily for greater than 48 weeks has been established, and daily use beyond 48 weeks has not been systematically and histologically investigated in adequate and well-controlled trials. (See WARNINGS section.) CLINICAL TRIALS DATA: Two adequate and well-controlled trials were conducted involving a total of 161 evaluable patients (under 50 years of age) treated with RENOVA and 154 evaluable patients treated with the vehicle emollient cream on the face for 24 weeks as an adjunct to a comprehensive skin care and sun avoidance program, to assess the effects on fine wrinkling, mottled hyperpigmentation, and tactile skin roughness. Patients were evaluated at baseline on a 10 point scale and changes from that baseline rating were categorized as follows: No Improvement: No change or an increase of 1 unit or more. Minimal Improvement: Reduction of 1 unit. Moderate Improvement: Reduction of 2 units or more. In these trials, the fine wrinkles, mottled hyperpigmentation, and tactile roughness of the facial skin were thought to be caused by multiple factors which included intrinsic aging or environmental factors, such as chronic sun exposure. The results of these assessments are as follows: FINE WRINKLING NO IMPROVEMENT MINIMAL IMPROVEMENT MODERATE IMPROVEMENT RENOVA + CSP* 36% 40% 24% Vehicle + CSP 62% 30% 8% MOTTLED HYPERPIGMENTATION NO IMPROVEMENT MINIMAL IMPROVEMENT MODERATE IMPROVEMENT RENOVA + CSP 35% 27% 38% Vehicle + CSP 53% 21 % 27% TACTILE SKIN ROUGHNESS *CSP = Comprehensive skin protection and sun avoidance programs including use of sunscreens, protective clothing, and emollient cream. NO IMPROVEMENT MINIMAL IMPROVEMENT MODERATE IMPROVEMENT RENOVA + CSP 49% 35% 16% Vehicle + CSP 67% 23% 10% Most of the improvement in these signs was noted during the first 24 weeks of therapy. Thereafter, therapy primarily maintained the improvement realized during the first 24 weeks. A majority of patients will lose most mitigating effects of RENOVA on fine wrinkles, mottled hyperpigmentation, and tactile roughness of facial skin with discontinuation of a comprehensive skin care and sun avoidance program including RENOVA; however, the safety and effectiveness of using RENOVA daily for greater than 48 weeks have not been established.

Is Renova | Tretinoin Cream usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Renova | Tretinoin Cream safe for breastfeeding
Active ingredient in Renova | Tretinoin Cream is Tretinoin and based on our analysis of Tretinoin it appears that using Renova | Tretinoin Cream is safe in breastfeeding. Below is analysis of Tretinoin while breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when RENOVA is administered to a nursing woman.

Renova | Tretinoin Cream Breastfeeding Analsys


Tretinoin while Breastfeeding

Safe

Retinoid, an acid form of vitamin A. At latest update no published data on excretion into breast milk were found.It is a normal component of breastmilk. Because of the small dose used and poor absorption into plasma of most topical dermatological preparations, excretion into breastmilk in significant amount appears to be unlikely. Do not apply on the breast, otherwise, wash it off thoroughly before next feed. Systemic use (overall as an antineoplastic drug) while breastfeeding is absolutely contraindicated.


Renova | Tretinoin Cream Breastfeeding Analsys - 2


Tretinoin while Breastfeeding

CAS Number: 302-79-4

Tretinoin has not been studied during breastfeeding. Breastfeeding should probably be avoided after oral use. Because it is poorly absorbed after topical application, it is considered a low risk to the nursing infant.[1][2][3] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[4]


Renova | Tretinoin Cream and breastfeeding

What if I already have used Renova | Tretinoin Cream?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Renova | Tretinoin Cream and have used it then do not panic as Renova | Tretinoin Cream is mostly safe in breastfeeding and should not cause any harm to your baby.


I am nursing mother and my doctor has suggested me to use Renova | Tretinoin Cream, is it safe?

Usage of Renova | Tretinoin Cream is safe for nursing mothers and baby, No worries.


If I am using Renova | Tretinoin Cream, will my baby need extra monitoring?

No


Who can I talk to if I have questions about usage of Renova | Tretinoin Cream in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week