Aminosyn while Breastfeeding

What is Aminosyn used for?

Is Aminosyn usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Isoleucine while Breastfeeding

CAS Number: 73-32-5

Leucine, isoleucine and valine are essential amino acids which are not produced by the body and must be ingested from the diet.They are found in large amount in muscles of meat and are necessary for synthesis of proteins in the body.They are wasted during liver disorders, high catabolic processes (cancer, burns) and also used for dietary supplementation in sport and fitness. At latest update no published data on excretion into breast milk were found.Around 20 amino acids (8 of them are essential) are normally present in breastmilk to which they reach through a selective-transport system of alveolar mammary epithelium (Ramirez 2001) with higher concentrations observed in the milk of obese mothers ( De Luca 2016).Its concentration is higher in the plasma of both mother and newborn after vaginal delivery than after cesarean section. (Schulpis 2009).BCAA supplementation does not alter the levels of prolactin (Bianchi 1992). These are natural components of the body that are devoid of toxicity even at higher doses than those recommended (AESAN 2012) without harmful effect while breastfeeding.

Leucine while Breastfeeding

CAS Number: 61-90-5

Leucine, isoleucine and valine are essential amino acids which are not produced by the body and must be ingested from the diet.They are found in large amount in muscles of meat and are necessary for synthesis of proteins in the body.They are wasted during liver disorders, high catabolic processes (cancer, burns) and also used for dietary supplementation in sport and fitness. At latest update no published data on excretion into breast milk were found.Around 20 amino acids (8 of them are essential) are normally present in breastmilk to which they reach through a selective-transport system of alveolar mammary epithelium (Ramirez 2001) with higher concentrations observed in the milk of obese mothers ( De Luca 2016).Its concentration is higher in the plasma of both mother and newborn after vaginal delivery than after cesarean section. (Schulpis 2009).BCAA supplementation does not alter the levels of prolactin (Bianchi 1992). These are natural components of the body that are devoid of toxicity even at higher doses than those recommended (AESAN 2012) without harmful effect while breastfeeding.

Lysine while Breastfeeding

CAS Number: 56-87-1

Lysine is an essential amino acid that is not produced by the body and must be taken from the diet.It is found in large amount in legumes, cereals, red meat, sea fish, cheese and eggs. It is crucial for the synthesis of proteins in the body and multiple metabolic functions.Often used as a dietary supplement without scientific evidence that would support any benefit of it. Breastmilk contains it naturally with a highest concentration in the colostrum followed by a decrease within the first month after birth (Harper 1984, 1986 Janas, Spevacek 2015).The concentration of lysine together with other amino acids and proteins is higher in the milk of mothers of preterm infants than in mothers of term infants (Atkinson 1980).Pasteurization slightly decreases the concentration of lysine and other amino acids (Silvestre 2006, Valentine 2010) but increases the amount of bioavailable lysine (Baro 2011). It is excreted into breast milk in clinically non-significant amount (0.5% of the administered dose) and as a part of proteins (Irving 1988, Thomas 1991).When used as a supplementation is considered to be safe during breastfeeding (Amir 2011, The Royal Women's Hospital Fact Sheet 2013)

Methionine while Breastfeeding

CAS Number: 63-68-3

Aminoacid used in the DL form to treat paracetamol intoxications. Also found in combination with other aminoacids in parenteral nutrition fluids.

Tryptophan while Breastfeeding

CAS Number: 73-22-3

Essential amino acid that is not produced by the body and must be taken from the diet.It is naturally found in many proteins of animal and plant origin (eggs, milk, cheese, soy, marine fish, nuts).It is a precursor of serotonin (George 1989, Yurcheshen 2015) through its metabolite 5-HTP or Oxitriptan (see card) and is credited with antioxidant properties (Tsopmo 2009).There is no conclusive scientific evidence that tryptophan supplements are effective on depression, insomnia, attention deficit, other diseases or improvement of physical performance (Yurcheshen 2015).It has been associated to a serious outbreak of Eosinophilia-Myalgia Syndrome with more than 1,500 cases and 37 deaths occurring in the 1990s, possibly caused by contaminated or poorly prepared batches of tryptophan (Falk 2011, Allen 2011, Sachs 2013, Yurcheshen 2015, Mediine Plus 2015). The FDA has launched a precautionary measure by withdrawing it from the market for years. At high doses it may cause side effects that are harmful to health (Fernstrom 2012). Tryptophan is a natural component of breast milk, with higher concentration in colostrum than in mature milk (Zarando 1989, Kamimura 1991) which is believed to have a circadian rhythm that regulates the sleep pattern and behavior of the infant ( Heine 1995, Cubero 2005).By taking tryptophan or alpha-lactalbumin (a high tryptophan-containing protein) tryptophan levels in breast milk is not increased (Dowlati 2015), but plasma prolactin concentration doest it (Chaney 1982, Cowen 1985) . With a comprehensive diet, tryptophan supplements are not needed at all, as their effectiveness has not been proven yet in any disease or disorder.Whenever used, a moderate consumption is recommended, making sure a reliable source since poisoning has been reported in the past.

Valine while Breastfeeding

CAS Number: 72-18-4

Leucine, isoleucine and valine are essential amino acids which are not produced by the body and must be ingested from the diet.They are found in large amount in muscles of meat and are necessary for synthesis of proteins in the body.They are wasted during liver disorders, high catabolic processes (cancer, burns) and also used for dietary supplementation in sport and fitness. At latest update no published data on excretion into breast milk were found.Around 20 amino acids (8 of them are essential) are normally present in breastmilk to which they reach through a selective-transport system of alveolar mammary epithelium (Ramirez 2001) with higher concentrations observed in the milk of obese mothers ( De Luca 2016).Its concentration is higher in the plasma of both mother and newborn after vaginal delivery than after cesarean section. (Schulpis 2009).BCAA supplementation does not alter the levels of prolactin (Bianchi 1992). These are natural components of the body that are devoid of toxicity even at higher doses than those recommended (AESAN 2012) without harmful effect while breastfeeding.

Arginine while Breastfeeding

CAS Number: 74-79-3

Amino acid which is present in meat and dairy products. It induces stimulation of Nitric Oxide production (vasodilation) and release of Insulin and Growth Hormone. Attributed benefit on health not confirmed. On latest update relevant data on breastfeeding was not found. Possibly not harmful while breastfeeding if abusive and continuous use is avoid.

I already used Aminosyn and meanwhile I breastfed my baby should I be concerned?

I am nursing mother and my doctor has suggested me to use Aminosyn, is it safe?

If I am using Aminosyn, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Aminosyn in breastfeeding?