Neostigmine Methylsulfate | Be Pharmaceuticals Inc. while Breastfeeding

It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Neostigmine Methylsulfate | Be Pharmaceuticals Inc. is safe for baby while breastfed.

What is Neostigmine Methylsulfate | Be Pharmaceuticals Inc. used for?


1 INDICATIONS & USAGE Neostigmine methylsulfate injection is a cholinesterase inhibitor indicated for the reversal of the effects of non-depolarizing neuromuscular blocking agents after surgery. Neostigmine methylsulfate injection, a cholinesterase inhibitor, is indicated for the reversal of the effects of non-depolarizing neuromuscular blocking agents (NMBAs) after surgery (1).

Is using Neostigmine Methylsulfate | Be Pharmaceuticals Inc. unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?

Neostigmine Methylsulfate | Be Pharmaceuticals Inc. safe for breastfeeding
Neostigmine methylsulfate is the only one ingredient used in manufacturing of Neostigmine Methylsulfate | Be Pharmaceuticals Inc., Which makes it easier to analyze its effect in breastfeeding. As per our analysis of Neostigmine methylsulfate it is safe to use Neostigmine Methylsulfate | Be Pharmaceuticals Inc. while lactating. We suggest you to check further details below about Neostigmine methylsulfate usage in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether neostigmine methylsulfate is excreted in human milk. Caution should be exercised when neostigmine methylsulfate injection is administered to a nursing woman.

Neostigmine Methylsulfate | Be Pharmaceuticals Inc. Breastfeeding Analsys


Neostigmine methylsulfate while Breastfeeding

Safe

CAS Number: 59-99-4

Reversible cholinesterase inhibitor used for treatment of Myasthenia gravis and as an analgesic adjuvant in epidural anesthesia (see specific info). It is not excreted into breastmilk (Fraser 1963, Wilson 1981).A breastfed neonate whose mother were treated with neostigmine suffered of abdominal colicky pain after a feeding, but the neostigmine plasma levels were undetectable (Fraser 1963). Because of a low oral bioavailability it seems even more unlikely the pass to the infant’s plasma through ingested breastmilk, except in preterm infants and immediate neonatal period, when there may be an increased intestinal permeability. On long-term treatments, because there is less published experience than with other drugs of the same group, a known safer alternative would be preferred during the neonatal period and/or in case of prematurity.


Neostigmine Methylsulfate | Be Pharmaceuticals Inc. Breastfeeding Analsys - 2


Neostigmine methylsulfate while Breastfeeding

CAS Number: 59-99-4

Limited data indicate that use of neostigmine to treat myasthenia gravis may be acceptable during breastfeeding, although pyridostigmine may be preferred. Monitor newborns because abdominal cramps after each breastfeeding has been reported. Because of its short half-life, single doses of neostigmine to reverse neuromuscular blockade following surgery are unlikely to adversely affect the breastfed infant more than transiently.


Neostigmine Methylsulfate | Be Pharmaceuticals Inc. and breastfeeding

What should I do if already breastfed my kid after using Neostigmine Methylsulfate | Be Pharmaceuticals Inc.?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Neostigmine Methylsulfate | Be Pharmaceuticals Inc. and have used it then do not panic as Neostigmine Methylsulfate | Be Pharmaceuticals Inc. is mostly safe in breastfeeding and should not cause any harm to your baby.


My health care provider has asked me to use Neostigmine Methylsulfate | Be Pharmaceuticals Inc., what to do?

Definitely, Neostigmine Methylsulfate | Be Pharmaceuticals Inc. is safe in lactation for baby. No wonder your doctor has recommended it.


If I am using Neostigmine Methylsulfate | Be Pharmaceuticals Inc., will my baby need extra monitoring?

No extra baby monitoring required while mother is using Neostigmine Methylsulfate | Be Pharmaceuticals Inc.


Who can I talk to if I have questions about usage of Neostigmine Methylsulfate | Be Pharmaceuticals Inc. in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week